Human Gene DRC1 (ENST00000288710.7) from GENCODE V44
Description: Homo sapiens dynein regulatory complex subunit 1 (DRC1), mRNA. (from RefSeq NM_145038) RefSeq Summary (NM_145038): This gene encodes a central component of the nexin-dynein complex (N-DRC), which regulates the assembly of ciliary dynein. Mutations in this gene can cause ciliary dyskinesia. [provided by RefSeq, Aug 2015]. Gencode Transcript: ENST00000288710.7 Gencode Gene: ENSG00000157856.12 Transcript (Including UTRs) Position: hg38 chr2:26,401,920-26,456,711 Size: 54,792 Total Exon Count: 17 Strand: + Coding Region Position: hg38 chr2:26,401,990-26,456,517 Size: 54,528 Coding Exon Count: 17
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q96MC2
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.