Human Gene STON1-GTF2A1L (ENST00000394754.5) from GENCODE V44
Description: Homo sapiens STON1-GTF2A1L readthrough (STON1-GTF2A1L), transcript variant 1, mRNA. (from RefSeq NM_172311) RefSeq Summary (NM_172311): STON1-GTF2A1L mRNAs are infrequent but naturally occurring read-through products of the neighboring STON1 and GTF2A1L genes. These transcripts encode fusion proteins composed of the vast majority of each of the individual elements, stonin 1 and general transcription factor IIA, 1-like. Alternative splicing results in multiple transcript variants. The significance of these read-through variants and the function of the resulting protein products have not yet been determined. [provided by RefSeq, Oct 2010]. Gencode Transcript: ENST00000394754.5 Gencode Gene: ENSG00000068781.21 Transcript (Including UTRs) Position: hg38 chr2:48,569,020-48,679,603 Size: 110,584 Total Exon Count: 11 Strand: + Coding Region Position: hg38 chr2:48,580,634-48,679,442 Size: 98,809 Coding Exon Count: 10
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00928 - Adaptor complexes medium subunit family PF03153 - Transcription factor IIA, alpha/beta subunit
ModBase Predicted Comparative 3D Structure on Q53S48
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006366 transcription from RNA polymerase II promoter GO:0006367 transcription initiation from RNA polymerase II promoter GO:0006897 endocytosis GO:0030100 regulation of endocytosis
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