Human Gene WIPF1 (ENST00000409415.7) from GENCODE V44
Description: Homo sapiens WAS/WASL interacting protein family member 1 (WIPF1), transcript variant 9, mRNA. (from RefSeq NM_001375838) RefSeq Summary (NM_001375836): This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000409415.7 Gencode Gene: ENSG00000115935.19 Transcript (Including UTRs) Position: hg38 chr2:174,571,169-174,682,871 Size: 111,703 Total Exon Count: 5 Strand: - Coding Region Position: hg38 chr2:174,571,593-174,585,573 Size: 13,981 Coding Exon Count: 4
ID:E9PB87_HUMAN DESCRIPTION: SubName: Full=WAS/WASL-interacting protein family member 1; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on E9PB87
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
