Human Gene ZFAND2B (ENST00000289528.10) from GENCODE V44
Description: Homo sapiens zinc finger AN1-type containing 2B (ZFAND2B), transcript variant 1, mRNA. (from RefSeq NM_138802) RefSeq Summary (NM_138802): This gene encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. The encoded protein likely associates with the proteosome to stimulate the degradation of toxic or misfolded proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]. Gencode Transcript: ENST00000289528.10 Gencode Gene: ENSG00000158552.13 Transcript (Including UTRs) Position: hg38 chr2:219,206,782-219,209,648 Size: 2,867 Total Exon Count: 9 Strand: + Coding Region Position: hg38 chr2:219,206,988-219,209,306 Size: 2,319 Coding Exon Count: 9
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8WV99
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043567 regulation of insulin-like growth factor receptor signaling pathway GO:0045047 protein targeting to ER