Human Gene DEFB121 (ENST00000376314.3) from GENCODE V44
Description: Homo sapiens defensin beta 121 (DEFB121), transcript variant 1, mRNA. (from RefSeq NM_001011878) RefSeq Summary (NM_001011878): This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]. Gencode Transcript: ENST00000376314.3 Gencode Gene: ENSG00000204548.4 Transcript (Including UTRs) Position: hg38 chr20:31,404,845-31,406,215 Size: 1,371 Total Exon Count: 2 Strand: - Coding Region Position: hg38 chr20:31,404,913-31,406,152 Size: 1,240 Coding Exon Count: 2
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q5J5C9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Gene Ontology (GO) Annotations with Structured Vocabulary