Human Gene TM9SF4 (ENST00000217315.9) from GENCODE V44
  Description: Homo sapiens transmembrane 9 superfamily member 4 (TM9SF4), transcript variant 2, mRNA. (from RefSeq NM_001363731)
Gencode Transcript: ENST00000217315.9
Gencode Gene: ENSG00000101337.16
Transcript (Including UTRs)
   Position: hg38 chr20:32,109,736-32,167,258 Size: 57,523 Total Exon Count: 18 Strand: +
Coding Region
   Position: hg38 chr20:32,133,049-32,165,444 Size: 32,396 Coding Exon Count: 17 

Page IndexSequence and LinksPrimersMalaCardsCTDRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr20:32,109,736-32,167,258)mRNA (may differ from genome)Protein (625 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCLynxMalacardsMGIOMIMPubMed
UniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: TM9SF4
Diseases sorted by gene-association score: melanoma (3)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 26.89 RPKM in Cells - Cultured fibroblasts
Total median expression: 933.68 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -152.30340-0.448 Picture PostScript Text
3' UTR -586.401814-0.323 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGDEnsembl   
Protein SequenceProtein SequenceProtein Sequence   
AlignmentAlignmentAlignment   

-  Descriptions from all associated GenBank mRNAs
  AK294980 - Homo sapiens cDNA FLJ54092 complete cds, highly similar to Transmembrane 9 superfamily protein member 4.
AK126534 - Homo sapiens cDNA FLJ44570 fis, clone UTERU3011063, highly similar to Transmembrane 9 superfamily protein member 4.
AK302439 - Homo sapiens cDNA FLJ54711 complete cds, highly similar to Transmembrane 9 superfamily protein member 4.
AK296500 - Homo sapiens cDNA FLJ53349 complete cds, highly similar to Transmembrane 9 superfamily protein member 4.
BC021107 - Homo sapiens transmembrane 9 superfamily protein member 4, mRNA (cDNA clone MGC:31858 IMAGE:4896167), complete cds.
D87444 - Homo sapiens mRNA for KIAA0255 gene, partial cds.
JD462879 - Sequence 443903 from Patent EP1572962.
JD373488 - Sequence 354512 from Patent EP1572962.
JD116235 - Sequence 97259 from Patent EP1572962.
JD265206 - Sequence 246230 from Patent EP1572962.
JD134274 - Sequence 115298 from Patent EP1572962.
JD085479 - Sequence 66503 from Patent EP1572962.
JD116233 - Sequence 97257 from Patent EP1572962.
JD401103 - Sequence 382127 from Patent EP1572962.
JD159321 - Sequence 140345 from Patent EP1572962.
JD392764 - Sequence 373788 from Patent EP1572962.
JD399562 - Sequence 380586 from Patent EP1572962.
JD392616 - Sequence 373640 from Patent EP1572962.
JD324548 - Sequence 305572 from Patent EP1572962.
JD122882 - Sequence 103906 from Patent EP1572962.
BC005173 - Homo sapiens cDNA clone IMAGE:3507918, containing frame-shift errors.
BC022850 - Homo sapiens transmembrane 9 superfamily protein member 4, mRNA (cDNA clone IMAGE:4098679), partial cds.
AB527227 - Synthetic construct DNA, clone: pF1KA0255, Homo sapiens TM9SF4 gene for transmembrane 9 superfamily protein member 4, without stop codon, in Flexi system.
AK316293 - Homo sapiens cDNA, FLJ79192 complete cds, highly similar to Transmembrane 9 superfamily protein member 4.
AK124411 - Homo sapiens cDNA FLJ42420 fis, clone BLADE2002730.
JD559948 - Sequence 540972 from Patent EP1572962.
JD485120 - Sequence 466144 from Patent EP1572962.
JD538920 - Sequence 519944 from Patent EP1572962.
JD312651 - Sequence 293675 from Patent EP1572962.
JD368194 - Sequence 349218 from Patent EP1572962.
JD228347 - Sequence 209371 from Patent EP1572962.
JD496150 - Sequence 477174 from Patent EP1572962.
JD457773 - Sequence 438797 from Patent EP1572962.
JD360862 - Sequence 341886 from Patent EP1572962.
JD230171 - Sequence 211195 from Patent EP1572962.
JD132919 - Sequence 113943 from Patent EP1572962.
JD166857 - Sequence 147881 from Patent EP1572962.
JD519560 - Sequence 500584 from Patent EP1572962.
JD164641 - Sequence 145665 from Patent EP1572962.
JD105137 - Sequence 86161 from Patent EP1572962.
JD513327 - Sequence 494351 from Patent EP1572962.
JD068560 - Sequence 49584 from Patent EP1572962.
JD103869 - Sequence 84893 from Patent EP1572962.
JD049677 - Sequence 30701 from Patent EP1572962.
JD073672 - Sequence 54696 from Patent EP1572962.
JD062243 - Sequence 43267 from Patent EP1572962.
JD330431 - Sequence 311455 from Patent EP1572962.
JD101686 - Sequence 82710 from Patent EP1572962.
JD324955 - Sequence 305979 from Patent EP1572962.
JD369383 - Sequence 350407 from Patent EP1572962.
JD455361 - Sequence 436385 from Patent EP1572962.
JD416739 - Sequence 397763 from Patent EP1572962.
JD190290 - Sequence 171314 from Patent EP1572962.
JD124119 - Sequence 105143 from Patent EP1572962.
JD511281 - Sequence 492305 from Patent EP1572962.
JD055374 - Sequence 36398 from Patent EP1572962.
JD053920 - Sequence 34944 from Patent EP1572962.
JD364788 - Sequence 345812 from Patent EP1572962.
JD513678 - Sequence 494702 from Patent EP1572962.
JD320093 - Sequence 301117 from Patent EP1572962.
JD566707 - Sequence 547731 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A0C4DFM1, ENST00000217315.1, ENST00000217315.2, ENST00000217315.3, ENST00000217315.4, ENST00000217315.5, ENST00000217315.6, ENST00000217315.7, ENST00000217315.8, NM_001363731, uc002wxk.1, uc002wxk.2
UCSC ID: ENST00000217315.9
RefSeq Accession: NM_001363731
CCDS: CCDS13196.2

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.