Human Gene CDH26 (ENST00000348616.9) from GENCODE V44
Description: Homo sapiens cadherin 26 (CDH26), transcript variant d, non-coding RNA. (from RefSeq NR_145482) RefSeq Summary (NM_177980): This gene encodes a member of the cadherin protein family. Cadherins are a family of calcium-dependent adhesion molecules that mediate cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization, migration and differentiation. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This protein is expressed in gastrointestinal epithelial cells and may be upregulated during allergic inflammation. This protein interacts with alpha integrins and may also be involved in leukocyte migration and adhesion. [provided by RefSeq, Jan 2017]. Gencode Transcript: ENST00000348616.9 Gencode Gene: ENSG00000124215.17 Transcript (Including UTRs) Position: hg38 chr20:59,958,423-60,014,529 Size: 56,107 Total Exon Count: 18 Strand: + Coding Region Position: hg38 chr20:59,958,727-60,012,730 Size: 54,004 Coding Exon Count: 18
ID:CAD26_HUMAN DESCRIPTION: RecName: Full=Cadherin-like protein 26; AltName: Full=Cadherin-like protein VR20; Flags: Precursor; FUNCTION: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (By similarity). SIMILARITY: Contains 4 cadherin domains.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8IXH8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
