Human Gene POTED (ENST00000299443.6) from GENCODE V44
Description: Homo sapiens POTE ankyrin domain family member D (POTED), mRNA. (from RefSeq NM_174981)
Gencode Transcript: ENST00000299443.6
Gencode Gene: ENSG00000166351.11
Transcript (Including UTRs)
Position: hg38 chr21:13,609,777-13,645,823 Size: 36,047 Total Exon Count: 11 Strand: +
Coding Region
Position: hg38 chr21:13,610,229-13,641,566 Size: 31,338 Coding Exon Count: 11
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: POTED_HUMAN
DESCRIPTION: RecName: Full=POTE ankyrin domain family member D; AltName: Full=ANKRD26-like family B member 3; AltName: Full=Ankyrin repeat domain-containing protein 21; AltName: Full=Prostate, ovary, testis-expressed protein; Short=Protein POTE;
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.TISSUE SPECIFICITY: Expressed in prostate, ovary, testis, placenta and prostate cancer cell lines. Localizes to basal and terminal prostate epithelial cells.SIMILARITY: Belongs to the POTE family.SIMILARITY: Contains 6 ANK repeats.
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
C049584
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
C036990
2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
D019327
Copper Sulfate
C006253
pirinixic acid
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR002110 - Ankyrin_rpt
IPR020683 - Ankyrin_rpt-contain_dom
Pfam Domains: PF12796 - Ankyrin repeats (3 copies)
ModBase Predicted Comparative 3D Structure on Q86YR6
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AY172978 - Homo sapiens POTE mRNA, complete cds.BC166701 - Synthetic construct Homo sapiens clone IMAGE:100066427, MGC:195564 POTE ankyrin domain family, member D (POTED) mRNA, encodes complete protein.JD315124 - Sequence 296148 from Patent EP1572962.JD289498 - Sequence 270522 from Patent EP1572962.HZ481095 - JP 2015535430-A/1601: TERMINALLY MODIFIED RNA.HZ791026 - JP 2016504050-A/2771: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.JC513758 - Sequence 4011 from Patent WO2014113089.LQ071346 - Sequence 1670 from Patent EP2964234.MA644847 - JP 2017113010-A/2771: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.MA732731 - JP 2017140048-A/1601: TERMINALLY MODIFIED RNA.MA801900 - JP 2018183181-A/2771: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
Other Names for This Gene
Alternate Gene Symbols: A26B3, ANKRD21, C9JCF7, ENST00000299443.1, ENST00000299443.2, ENST00000299443.3, ENST00000299443.4, ENST00000299443.5, NM_174981, POTE, POTED_HUMAN, Q86YR6, uc002yjb.1, uc002yjb.2UCSC ID: ENST00000299443.6RefSeq Accession: NM_174981
Protein: Q86YR6
(aka POTED_HUMAN)
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.