Human Gene RARRES1 (ENST00000479756.1) from GENCODE V44
Description: Homo sapiens retinoic acid receptor responder 1 (RARRES1), transcript variant 2, mRNA. (from RefSeq NM_002888) RefSeq Summary (NM_002888): This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000479756.1 Gencode Gene: ENSG00000118849.10 Transcript (Including UTRs) Position: hg38 chr3:158,704,651-158,732,442 Size: 27,792 Total Exon Count: 4 Strand: - Coding Region Position: hg38 chr3:158,704,776-158,732,415 Size: 27,640 Coding Exon Count: 4
ID:TIG1_HUMAN DESCRIPTION: RecName: Full=Retinoic acid receptor responder protein 1; AltName: Full=RAR-responsive protein TIG1; AltName: Full=Tazarotene-induced gene 1 protein; SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein (Potential). INDUCTION: By tazarotene and by all the retinoic acid receptors tested. SIMILARITY: Belongs to the protease inhibitor I47 (latexin) family. WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/RARRES1ID42050ch3q25.html";
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P49788
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
