Human Gene MRFAP1L1 (ENST00000320848.7) from GENCODE V44
  Description: Homo sapiens Morf4 family associated protein 1 like 1 (MRFAP1L1), mRNA. (from RefSeq NM_203462)
Gencode Transcript: ENST00000320848.7
Gencode Gene: ENSG00000178988.11
Transcript (Including UTRs)
   Position: hg38 chr4:6,707,701-6,709,865 Size: 2,165 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg38 chr4:6,709,246-6,709,629 Size: 384 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:6,707,701-6,709,865)mRNA (may differ from genome)Protein (127 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCHPRDLynxMalacardsMGIneXtProt
PubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: MR1L1_HUMAN
DESCRIPTION: RecName: Full=MORF4 family-associated protein 1-like 1;
SIMILARITY: Belongs to the MORF4 family-associated protein family.
SEQUENCE CAUTION: Sequence=AAF67011.1; Type=Frameshift; Positions=89;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 71.81 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 1972.79 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -69.20236-0.293 Picture PostScript Text
3' UTR -235.40958-0.246 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q96HT8
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding
GO:0042802 identical protein binding


-  Descriptions from all associated GenBank mRNAs
  BC008087 - Homo sapiens Morf4 family associated protein 1-like 1, mRNA (cDNA clone MGC:9651 IMAGE:3446352), complete cds.
AF258591 - Homo sapiens PP784 mRNA, complete cds.
AF155654 - Human putative ribosomal protein S1 mRNA.
BC066897 - Homo sapiens Morf4 family associated protein 1-like 1, mRNA (cDNA clone MGC:86990 IMAGE:4818881), complete cds.
JD109184 - Sequence 90208 from Patent EP1572962.
JD515439 - Sequence 496463 from Patent EP1572962.
JD539070 - Sequence 520094 from Patent EP1572962.
JD483499 - Sequence 464523 from Patent EP1572962.
JD060300 - Sequence 41324 from Patent EP1572962.
JD266215 - Sequence 247239 from Patent EP1572962.
JD140305 - Sequence 121329 from Patent EP1572962.
JD058917 - Sequence 39941 from Patent EP1572962.
JD078995 - Sequence 60019 from Patent EP1572962.
JD171742 - Sequence 152766 from Patent EP1572962.
JD233874 - Sequence 214898 from Patent EP1572962.
JD289224 - Sequence 270248 from Patent EP1572962.
KC858143 - Homo sapiens MRFAP1L1 mRNA, complete cds.
AK312676 - Homo sapiens cDNA, FLJ93069.
HQ447948 - Synthetic construct Homo sapiens clone IMAGE:100071310; CCSB002777_01 Morf4 family associated protein 1-like 1 (MRFAP1L1) gene, encodes complete protein.
KJ895276 - Synthetic construct Homo sapiens clone ccsbBroadEn_04670 MRFAP1L1 gene, encodes complete protein.
KJ900013 - Synthetic construct Homo sapiens clone ccsbBroadEn_09407 MRFAP1L1 gene, encodes complete protein.
AB464624 - Synthetic construct DNA, clone: pF1KB8744, Homo sapiens MRFAP1L1 gene for Morf4 family associated protein 1-like 1, without stop codon, in Flexi system.
JD423280 - Sequence 404304 from Patent EP1572962.
JD352699 - Sequence 333723 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B2R6R0, ENST00000320848.1, ENST00000320848.2, ENST00000320848.3, ENST00000320848.4, ENST00000320848.5, ENST00000320848.6, MR1L1_HUMAN, NM_203462, PP784, Q6NXT8, Q96HT8, Q9P0J5, uc003gjo.1, uc003gjo.2, uc003gjo.3, uc003gjo.4, uc003gjo.5, uc003gjo.6
UCSC ID: ENST00000320848.7
RefSeq Accession: NM_203462
Protein: Q96HT8 (aka MR1L1_HUMAN)
CCDS: CCDS3392.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.