Human Gene SPINK2 (ENST00000248701.8) from GENCODE V44
Description: Homo sapiens serine peptidase inhibitor Kazal type 2 (SPINK2), transcript variant 2, mRNA. (from RefSeq NM_021114) RefSeq Summary (NM_021114): This gene encodes a member of the family of serine protease inhibitors of the Kazal type (SPINK). The encoded protein acts as a trypsin and acrosin inhibitor in the genital tract and is localized in the spermatozoa. The protein has been associated with the progression of lymphomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]. Gencode Transcript: ENST00000248701.8 Gencode Gene: ENSG00000128040.13 Transcript (Including UTRs) Position: hg38 chr4:56,809,861-56,821,742 Size: 11,882 Total Exon Count: 4 Strand: - Coding Region Position: hg38 chr4:56,810,139-56,821,662 Size: 11,524 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P20155
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
