Human Gene CEP44 (ENST00000503780.6) from GENCODE V44
  Description: Homo sapiens centrosomal protein 44 (CEP44), transcript variant 1, mRNA. (from RefSeq NM_001040157)
Gencode Transcript: ENST00000503780.6
Gencode Gene: ENSG00000164118.13
Transcript (Including UTRs)
   Position: hg38 chr4:174,283,911-174,320,328 Size: 36,418 Total Exon Count: 12 Strand: +
Coding Region
   Position: hg38 chr4:174,299,122-174,317,383 Size: 18,262 Coding Exon Count: 10 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:174,283,911-174,320,328)mRNA (may differ from genome)Protein (390 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCLynxMalacardsMGIneXtProtPubMed
UniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: CEP44_HUMAN
DESCRIPTION: RecName: Full=Centrosomal protein of 44 kDa; AltName: Full=HBV PreS1-transactivated protein 3; Short=PS1TP3;
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody. Note=Localizes to centrosomes, spindle poles, and weakly in midbody.
SEQUENCE CAUTION: Sequence=BAB21803.1; Type=Erroneous initiation;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 5.36 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 159.45 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -46.50180-0.258 Picture PostScript Text
3' UTR -716.402945-0.243 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q9C0F1
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

Cellular Component:
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005856 cytoskeleton
GO:0030496 midbody


-  Descriptions from all associated GenBank mRNAs
  BC038667 - Homo sapiens KIAA1712, mRNA (cDNA clone MGC:33587 IMAGE:4823994), complete cds.
AK292484 - Homo sapiens cDNA FLJ78628 complete cds.
AK094961 - Homo sapiens cDNA FLJ37642 fis, clone BRHIP2000163.
KJ904892 - Synthetic construct Homo sapiens clone ccsbBroadEn_14286 CEP44 gene, encodes complete protein.
JD064781 - Sequence 45805 from Patent EP1572962.
JD415582 - Sequence 396606 from Patent EP1572962.
AB051499 - Homo sapiens KIAA1712 mRNA for KIAA1712 protein.
JD305766 - Sequence 286790 from Patent EP1572962.
AB384268 - Synthetic construct DNA, clone: pF1KSDA1712, Homo sapiens KIAA1712 gene for KIAA1712 protein, complete cds, without stop codon, in Flexi system.
AY426674 - Homo sapiens HBV PreS1-transactivated protein 3 mRNA, complete cds.
JD073311 - Sequence 54335 from Patent EP1572962.
JD112921 - Sequence 93945 from Patent EP1572962.
JD357103 - Sequence 338127 from Patent EP1572962.
JD485434 - Sequence 466458 from Patent EP1572962.
JD482338 - Sequence 463362 from Patent EP1572962.
JD300697 - Sequence 281721 from Patent EP1572962.
JD292083 - Sequence 273107 from Patent EP1572962.
JD181570 - Sequence 162594 from Patent EP1572962.
JD428587 - Sequence 409611 from Patent EP1572962.
JD550731 - Sequence 531755 from Patent EP1572962.
JD293309 - Sequence 274333 from Patent EP1572962.
JD087024 - Sequence 68048 from Patent EP1572962.
JD262025 - Sequence 243049 from Patent EP1572962.
JD432400 - Sequence 413424 from Patent EP1572962.
JD560905 - Sequence 541929 from Patent EP1572962.
JD542644 - Sequence 523668 from Patent EP1572962.
JD212574 - Sequence 193598 from Patent EP1572962.
JD553426 - Sequence 534450 from Patent EP1572962.
JD325193 - Sequence 306217 from Patent EP1572962.
JD091427 - Sequence 72451 from Patent EP1572962.
JD549557 - Sequence 530581 from Patent EP1572962.
JD566779 - Sequence 547803 from Patent EP1572962.
JD263385 - Sequence 244409 from Patent EP1572962.
JD413613 - Sequence 394637 from Patent EP1572962.
JD367075 - Sequence 348099 from Patent EP1572962.
JD325560 - Sequence 306584 from Patent EP1572962.
JD418044 - Sequence 399068 from Patent EP1572962.
JD147301 - Sequence 128325 from Patent EP1572962.
JD293349 - Sequence 274373 from Patent EP1572962.
JD457468 - Sequence 438492 from Patent EP1572962.
JD388882 - Sequence 369906 from Patent EP1572962.
JD353084 - Sequence 334108 from Patent EP1572962.
JD353085 - Sequence 334109 from Patent EP1572962.
JD258819 - Sequence 239843 from Patent EP1572962.
JD152340 - Sequence 133364 from Patent EP1572962.
JD256843 - Sequence 237867 from Patent EP1572962.
JD407664 - Sequence 388688 from Patent EP1572962.
JD461009 - Sequence 442033 from Patent EP1572962.
JD119886 - Sequence 100910 from Patent EP1572962.
JD385127 - Sequence 366151 from Patent EP1572962.
JD417313 - Sequence 398337 from Patent EP1572962.
JD333638 - Sequence 314662 from Patent EP1572962.
JD251652 - Sequence 232676 from Patent EP1572962.
BC045590 - Homo sapiens cDNA clone IMAGE:5276927.
JD114097 - Sequence 95121 from Patent EP1572962.
JD187904 - Sequence 168928 from Patent EP1572962.
JD384936 - Sequence 365960 from Patent EP1572962.
JD042346 - Sequence 23370 from Patent EP1572962.
JD313141 - Sequence 294165 from Patent EP1572962.
JD304736 - Sequence 285760 from Patent EP1572962.
JD047077 - Sequence 28101 from Patent EP1572962.
JD067117 - Sequence 48141 from Patent EP1572962.
JD558175 - Sequence 539199 from Patent EP1572962.
JD221306 - Sequence 202330 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A8K8W9, A8MW11, B3KT53, CEP44_HUMAN, D3DP42, ENST00000503780.1, ENST00000503780.2, ENST00000503780.3, ENST00000503780.4, ENST00000503780.5, KIAA1712, NM_001040157, Q8IXZ4, Q9C0F1, uc003itr.1, uc003itr.2, uc003itr.3, uc003itr.4, uc003itr.5
UCSC ID: ENST00000503780.6
RefSeq Accession: NM_001040157
Protein: Q9C0F1 (aka CEP44_HUMAN)
CCDS: CCDS34106.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.