Human Gene APOM (ENST00000375920.8) from GENCODE V44
Description: Homo sapiens apolipoprotein M (APOM), transcript variant 3, non-coding RNA. (from RefSeq NR_045828) RefSeq Summary (NM_001256169): The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]. Gencode Transcript: ENST00000375920.8 Gencode Gene: ENSG00000204444.11 Transcript (Including UTRs) Position: hg38 chr6:31,652,417-31,658,210 Size: 5,794 Total Exon Count: 6 Strand: + Coding Region Position: hg38 chr6:31,656,574-31,658,089 Size: 1,516 Coding Exon Count: 5
ID:APOM_HUMAN DESCRIPTION: RecName: Full=Apolipoprotein M; Short=Apo-M; Short=ApoM; AltName: Full=Protein G3a; FUNCTION: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. SUBCELLULAR LOCATION: Secreted. Note=Present in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins (LDL). TISSUE SPECIFICITY: Plasma protein. Expressed in liver and kidney. SIMILARITY: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O95445
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.