Human Gene SNX14 (ENST00000346348.7) from GENCODE V44
Description: Homo sapiens sorting nexin 14 (SNX14), transcript variant 2, mRNA. (from RefSeq NM_020468) RefSeq Summary (NM_020468): This gene encodes a member of the sorting nexin family. Members of this family have a phox (PX) phosphoinositide binding domain and are involved in intracellular trafficking. The encoded protein also contains a regulator of G protein signaling (RGS) domain. Regulator of G protein signaling family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. Alternate splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]. Gencode Transcript: ENST00000346348.7 Gencode Gene: ENSG00000135317.14 Transcript (Including UTRs) Position: hg38 chr6:85,505,496-85,593,913 Size: 88,418 Total Exon Count: 26 Strand: - Coding Region Position: hg38 chr6:85,505,967-85,593,718 Size: 87,752 Coding Exon Count: 26
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF08628 - Sorting nexin C terminal PF00787 - PX domain PF02194 - PXA domain PF00615 - Regulator of G protein signaling domain
ModBase Predicted Comparative 3D Structure on Q9Y5W7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
