Human Gene FBXL6 (ENST00000331890.6) from GENCODE V44
Description: Homo sapiens F-box and leucine rich repeat protein 6 (FBXL6), transcript variant 1, mRNA. (from RefSeq NM_012162) RefSeq Summary (NM_012162): This gene encodes a member of a family of proteins that are characterized by an F-box motif. The encoded protein also contains leucine-rich repeats. F-box-containing proteins comprise one of the subunits of the SCF (SKP1-cullin-F-box) complex, which functions in phosphorylation-dependent ubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]. Gencode Transcript: ENST00000331890.6 Gencode Gene: ENSG00000182325.11 Transcript (Including UTRs) Position: hg38 chr8:144,355,431-144,358,472 Size: 3,042 Total Exon Count: 9 Strand: - Coding Region Position: hg38 chr8:144,355,531-144,358,447 Size: 2,917 Coding Exon Count: 9
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8N531
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
