ID:CAAP1_HUMAN DESCRIPTION: RecName: Full=Caspase activity and apoptosis inhibitor 1; AltName: Full=Conserved anti-apoptotic protein; Short=CAAP; FUNCTION: Anti-apoptotic protein that modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop. TISSUE SPECIFICITY: Ubiquitous. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q9H8G2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
