Human Gene ARMCX1 (ENST00000372829.8) from GENCODE V44
Description: Homo sapiens armadillo repeat containing X-linked 1 (ARMCX1), mRNA. (from RefSeq NM_016608) RefSeq Summary (NM_016608): This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000372829.8 Gencode Gene: ENSG00000126947.13 Transcript (Including UTRs) Position: hg38 chrX:101,550,547-101,554,700 Size: 4,154 Total Exon Count: 4 Strand: + Coding Region Position: hg38 chrX:101,552,931-101,554,292 Size: 1,362 Coding Exon Count: 1
ID:ARMX1_HUMAN DESCRIPTION: RecName: Full=Armadillo repeat-containing X-linked protein 1; AltName: Full=ARM protein lost in epithelial cancers on chromosome X 1; Short=Protein ALEX1; SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential). TISSUE SPECIFICITY: Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas. SIMILARITY: Contains 3 ARM repeats. SEQUENCE CAUTION: Sequence=AAG44561.1; Type=Frameshift; Positions=357, 370; WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/ALEX1Xq22ID477.html";
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9P291
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
