Human Gene AXDND1 (ENST00000511157.5) from GENCODE V44
  Description: Homo sapiens axonemal dynein light chain domain containing 1 (AXDND1), transcript variant 2, non-coding RNA. (from RefSeq NR_073544)
Gencode Transcript: ENST00000511157.5
Gencode Gene: ENSG00000162779.22
Transcript (Including UTRs)
   Position: hg38 chr1:179,365,972-179,554,735 Size: 188,764 Total Exon Count: 26 Strand: +
Coding Region
   Position: hg38 chr1:179,366,510-179,468,469 Size: 101,960 Coding Exon Count: 15 

Page IndexSequence and LinksPrimersCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:179,365,972-179,554,735)mRNA (may differ from genome)Protein (529 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGencodeGeneCardsHGNC
LynxMalacardsMGIPubMedUniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 9.77 RPKM in Testis
Total median expression: 12.27 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -94.70261-0.363 Picture PostScript Text
3' UTR -360.501524-0.237 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR019347 - Axonemal_dynein_light_chain

Pfam Domains:
PF10211 - Axonemal dynein light chain

ModBase Predicted Comparative 3D Structure on A6H900
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGI     
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  BX647935 - Homo sapiens mRNA; cDNA DKFZp686H1423 (from clone DKFZp686H1423).
AK302972 - Homo sapiens cDNA FLJ61642 complete cds.
BC146823 - Homo sapiens chromosome 1 open reading frame 125, mRNA (cDNA clone MGC:167105 IMAGE:8860438), complete cds.
AK057502 - Homo sapiens cDNA FLJ32940 fis, clone TESTI2007750.
KJ903728 - Synthetic construct Homo sapiens clone ccsbBroadEn_13122 AXDND1 gene, encodes complete protein.
KJ905606 - Synthetic construct Homo sapiens clone ccsbBroadEn_15237 AXDND1 gene, encodes complete protein.
AL833914 - Homo sapiens mRNA; cDNA DKFZp434N1720 (from clone DKFZp434N1720).
JD350139 - Sequence 331163 from Patent EP1572962.
JD131413 - Sequence 112437 from Patent EP1572962.
JD331640 - Sequence 312664 from Patent EP1572962.
JD305113 - Sequence 286137 from Patent EP1572962.
JD048437 - Sequence 29461 from Patent EP1572962.
JD037109 - Sequence 18133 from Patent EP1572962.
JD137296 - Sequence 118320 from Patent EP1572962.
AK058167 - Homo sapiens cDNA FLJ25438 fis, clone TST08327.
JD482386 - Sequence 463410 from Patent EP1572962.
JD053252 - Sequence 34276 from Patent EP1572962.
JD263334 - Sequence 244358 from Patent EP1572962.
JD074690 - Sequence 55714 from Patent EP1572962.
JD206157 - Sequence 187181 from Patent EP1572962.
JD094583 - Sequence 75607 from Patent EP1572962.
JD095915 - Sequence 76939 from Patent EP1572962.
JD435972 - Sequence 416996 from Patent EP1572962.
AK093460 - Homo sapiens cDNA FLJ36141 fis, clone TESTI2024978.
JD498218 - Sequence 479242 from Patent EP1572962.
JD500913 - Sequence 481937 from Patent EP1572962.
JD195196 - Sequence 176220 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A6H900, A6H900_HUMAN, C1orf125, ENST00000511157.1, ENST00000511157.2, ENST00000511157.3, ENST00000511157.4, NR_073544, uc009wxg.1, uc009wxg.2, uc009wxg.3, uc009wxg.4
UCSC ID: ENST00000511157.5
RefSeq Accession: NR_073544
Protein: A6H900

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.