Human Gene KLRD1 (ENST00000543777.5) from GENCODE V44
Description: Homo sapiens killer cell lectin like receptor D1 (KLRD1), transcript variant 6, mRNA. (from RefSeq NM_001351063) RefSeq Summary (NM_001351063): Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]. Gencode Transcript: ENST00000543777.5 Gencode Gene: ENSG00000134539.17 Transcript (Including UTRs) Position: hg38 chr12:10,307,950-10,314,977 Size: 7,028 Total Exon Count: 5 Strand: + Coding Region Position: hg38 chr12:10,308,078-10,314,793 Size: 6,716 Coding Exon Count: 5
ID:F6WZH4_HUMAN DESCRIPTION: SubName: Full=Natural killer cells antigen CD94; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on F6WZH4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
