Human Gene TEP1 (ENST00000555008.5) from GENCODE V44
Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt G3V2A4) RefSeq Summary (NM_001319035): This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]. Gencode Transcript: ENST00000555008.5 Gencode Gene: ENSG00000129566.13 Transcript (Including UTRs) Position: hg38 chr14:20,367,631-20,391,745 Size: 24,115 Total Exon Count: 43 Strand: - Coding Region Position: hg38 chr14:20,368,851-20,391,745 Size: 22,895 Coding Exon Count: 42
ID:G3V2A4_HUMAN DESCRIPTION: SubName: Full=Telomerase protein component 1; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF13271 - Domain of unknown function (DUF4062) PF00400 - WD domain, G-beta repeat
ModBase Predicted Comparative 3D Structure on G3V2A4
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.