Human Gene RLN3 (ENST00000585987.1) from GENCODE V44
Description: Homo sapiens relaxin 3 (RLN3), transcript variant 2, mRNA. (from RefSeq NM_001311197) RefSeq Summary (NM_001311197): This gene encodes a member of the relaxin family of insulin-like hormones that is expressed predominantly in the brain and plays a role in physiological processes such as stress, memory and appetite regulation. The encoded protein is a precursor that is proteolytically processed to generate a heterodimeric mature form consisting A and B chains interlinked by disulfide bonds. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]. Gencode Transcript: ENST00000585987.1 Gencode Gene: ENSG00000171136.7 Transcript (Including UTRs) Position: hg38 chr19:14,028,205-14,030,948 Size: 2,744 Total Exon Count: 3 Strand: + Coding Region Position: hg38 chr19:14,028,205-14,030,737 Size: 2,533 Coding Exon Count: 3
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.