Human Gene IL1R1 (ENST00000409929.5) from GENCODE V44
Description: Homo sapiens interleukin 1 receptor type 1 (IL1R1), transcript variant 2, mRNA. (from RefSeq NM_001288706) RefSeq Summary (NM_001288706): This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013]. Gencode Transcript: ENST00000409929.5 Gencode Gene: ENSG00000115594.12 Transcript (Including UTRs) Position: hg38 chr2:102,070,376-102,176,759 Size: 106,384 Total Exon Count: 12 Strand: + Coding Region Position: hg38 chr2:102,157,725-102,176,759 Size: 19,035 Coding Exon Count: 10
ID:B8ZZW4_HUMAN DESCRIPTION: SubName: Full=Interleukin-1 receptor type 1, soluble form; SIMILARITY: Contains 1 TIR domain. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on B8ZZW4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
