Human Gene DSCR8 (ENST00000478613.5) from GENCODE V44
  Description: Homo sapiens Down syndrome critical region 8 (DSCR8), transcript variant 3, long non-coding RNA. (from RefSeq NR_026839)
Gencode Transcript: ENST00000478613.5
Gencode Gene: ENSG00000198054.12
Transcript (Including UTRs)
   Position: hg38 chr21:38,121,451-38,156,511 Size: 35,061 Total Exon Count: 3 Strand: +


Page IndexSequence and LinksPrimersMalaCardsRNA-Seq ExpressionMicroarray Expression
Other SpeciesmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr21:38,121,451-38,156,511)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
EnsemblEntrez GeneExonPrimerGencodeHGNCLynx
MalacardsOMIMPubMedBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: DSCR8
Diseases sorted by gene-association score: down syndrome (13)

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 20.50 RPKM in Testis
Total median expression: 20.52 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC029353 - Homo sapiens Down syndrome critical region gene 8, mRNA (cDNA clone IMAGE:4659328).
AJ297914 - Homo sapiens mRNA for malignant melanoma associated protein 1a (MMA-1a gene).
AJ301615 - Homo sapiens mRNA for malignant melanoma associated protein, alternative splice variant MMA-1b, (MMA-1 gene).
AJ305085 - Homo sapiens mRNA for malignant melanoma associated protein, splice variant 1e (MMA-1 gene).
AJ306839 - Homo sapiens mRNA for malignant melanoma associated protein (MMA-1 gene), splice variant MMA-1c.
AJ306840 - Homo sapiens mRNA for malignant melanoma associated protein (MMA-1 gene), splice variant MMA-1f.
AJ783421 - Homo sapiens mRNA for malignant melanoma associated protein (MMA-1 gene), splice variant MMA-1d.
BC015981 - Homo sapiens Down syndrome critical region gene 8, mRNA (cDNA clone IMAGE:4064987).
AF321193 - Homo sapiens down syndrome critical region protein DSCR8 (DSCR8) mRNA, complete cds.
BC070229 - Homo sapiens Down syndrome critical region gene 8, mRNA (cDNA clone IMAGE:4762971).
AJ001904 - Homo sapiens cDNA selection product, DCR1-24.0.
BC117304 - Homo sapiens Down syndrome critical region gene 8, mRNA (cDNA clone IMAGE:40125855).
BC117330 - Homo sapiens Down syndrome critical region gene 8, mRNA (cDNA clone IMAGE:40125881).
BC143995 - Homo sapiens Down syndrome critical region gene 8, mRNA (cDNA clone IMAGE:9052513).
AF426256 - Homo sapiens DSCR8 protein (DSCR8) mRNA, complete cds.
KJ900873 - Synthetic construct Homo sapiens clone ccsbBroadEn_10267 DSCR8 gene, encodes complete protein.
KJ900874 - Synthetic construct Homo sapiens clone ccsbBroadEn_10268 DSCR8 gene, encodes complete protein.
JD160179 - Sequence 141203 from Patent EP1572962.
JD088474 - Sequence 69498 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000478613.1, ENST00000478613.2, ENST00000478613.3, ENST00000478613.4, NR_026839, uc010gnr.1, uc010gnr.2, uc010gnr.3
UCSC ID: ENST00000478613.5
RefSeq Accession: NR_026839

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.