Human Gene TBC1D22A (ENST00000380995.5) from GENCODE V44
  Description: Homo sapiens TBC1 domain family member 22A (TBC1D22A), transcript variant 3, mRNA. (from RefSeq NM_001284304)
Gencode Transcript: ENST00000380995.5
Gencode Gene: ENSG00000054611.14
Transcript (Including UTRs)
   Position: hg38 chr22:46,762,617-47,175,699 Size: 413,083 Total Exon Count: 14 Strand: +
Coding Region
   Position: hg38 chr22:46,792,776-47,173,626 Size: 380,851 Coding Exon Count: 12 

Page IndexSequence and LinksPrimersCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr22:46,762,617-47,175,699)mRNA (may differ from genome)Protein (487 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCLynxMalacardsMGIOMIMPubMed
UniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 15.97 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 317.92 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -162.20397-0.409 Picture PostScript Text
3' UTR -870.902073-0.420 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  LF385067 - JP 2014500723-A/192570: Polycomb-Associated Non-Coding RNAs.
MA620644 - JP 2018138019-A/192570: Polycomb-Associated Non-Coding RNAs.
AK055591 - Homo sapiens cDNA FLJ31029 fis, clone HSYRA1000119, highly similar to TBC1 domain family member 22A.
AK301445 - Homo sapiens cDNA FLJ57214 complete cds, highly similar to TBC1 domain family member 22A.
BC029897 - Homo sapiens TBC1 domain family, member 22A, mRNA (cDNA clone MGC:35253 IMAGE:5173045), complete cds.
AK315779 - Homo sapiens cDNA, FLJ96895, highly similar to Homo sapiens TBC1 domain family, member 22A (TBC1D22A), mRNA.
BC002743 - Homo sapiens TBC1 domain family, member 22A, mRNA (cDNA clone MGC:3547 IMAGE:3627634), complete cds.
BC020976 - Homo sapiens TBC1 domain family, member 22A, mRNA (cDNA clone MGC:9583 IMAGE:3884347), complete cds.
BC001292 - Homo sapiens TBC1 domain family, member 22A, mRNA (cDNA clone MGC:5258 IMAGE:3457393), complete cds.
AK308039 - Homo sapiens cDNA, FLJ97987.
CR456412 - Homo sapiens C22orf4 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.C22orf4).
CU013260 - Homo sapiens TBC1D22A, mRNA (cDNA clone IMAGE:100000038), complete cds, without stop codon, in Gateway system.
CU012972 - Homo sapiens TBC1D22A, mRNA (cDNA clone IMAGE:100000134), complete cds, with stop codon, in Gateway system.
AB587482 - Synthetic construct DNA, clone: pF1KB8643, Homo sapiens TBC1D22A gene for TBC1 domain family, member 22A, without stop codon, in Flexi system.
CU678158 - Synthetic construct Homo sapiens gateway clone IMAGE:100017271 5' read TBC1D22A mRNA.
KJ902371 - Synthetic construct Homo sapiens clone ccsbBroadEn_11765 TBC1D22A gene, encodes complete protein.
AB449908 - Homo sapiens TBC1D22A mRNA for TBC1 domain family, member 22A, complete cds.
AK125705 - Homo sapiens cDNA FLJ43717 fis, clone TESOP2005579.
AK127653 - Homo sapiens cDNA FLJ45751 fis, clone LYMPB2002344, highly similar to TBC1 domain family member 22A.
AL096779 - Novel human gene mapping to chomosome 22q13.3 similar to yeast ORF YOR070C, putative GTPase Activator (start missing).
AK000851 - Homo sapiens cDNA FLJ20844 fis, clone ADKA01904.
JD077272 - Sequence 58296 from Patent EP1572962.
JD408791 - Sequence 389815 from Patent EP1572962.
JD425695 - Sequence 406719 from Patent EP1572962.
JD195964 - Sequence 176988 from Patent EP1572962.
JD043042 - Sequence 24066 from Patent EP1572962.
JD219597 - Sequence 200621 from Patent EP1572962.
JD484434 - Sequence 465458 from Patent EP1572962.
JD565463 - Sequence 546487 from Patent EP1572962.
JD243667 - Sequence 224691 from Patent EP1572962.
BC022417 - Homo sapiens cDNA clone IMAGE:4243782, partial cds.
JD466005 - Sequence 447029 from Patent EP1572962.
JD560119 - Sequence 541143 from Patent EP1572962.
JD480777 - Sequence 461801 from Patent EP1572962.
JD521313 - Sequence 502337 from Patent EP1572962.
JD210734 - Sequence 191758 from Patent EP1572962.
JD518617 - Sequence 499641 from Patent EP1572962.
JD406346 - Sequence 387370 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A0A0MRY0, ENST00000380995.1, ENST00000380995.2, ENST00000380995.3, ENST00000380995.4, NM_001284304, uc010haf.1, uc010haf.2, uc010haf.3, uc010haf.4
UCSC ID: ENST00000380995.5
RefSeq Accession: NM_001284304
CCDS: CCDS63512.1, CCDS74877.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.