Human Gene SLC10A7 (ENST00000432059.6) from GENCODE V44
Description: Homo sapiens solute carrier family 10 member 7 (SLC10A7), transcript variant 5, mRNA. (from RefSeq NM_001317816)
Gencode Transcript: ENST00000432059.6
Gencode Gene: ENSG00000120519.16
Transcript (Including UTRs)
Position: hg38 chr4:146,253,975-146,521,964 Size: 267,990 Total Exon Count: 11 Strand: -
Coding Region
Position: hg38 chr4:146,256,491-146,521,717 Size: 265,227 Coding Exon Count: 11
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: NTCP7_HUMAN
DESCRIPTION: RecName: Full=Sodium/bile acid cotransporter 7; AltName: Full=Na(+)/bile acid cotransporter 7; AltName: Full=Solute carrier family 10 member 7;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).SIMILARITY: Belongs to the unknown BART superfamily-1 (UBS1) (TC 2.A.93) family.SEQUENCE CAUTION: Sequence=BAC11571.1; Type=Erroneous initiation;
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR016833 - Put_Na-Bile_cotransptr
Pfam Domains: PF13593 - SBF-like CPA transporter family (DUF4137)
ModBase Predicted Comparative 3D Structure on Q0GE19
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
EU831740 - Synthetic construct Homo sapiens clone HAIB:100066769; DKFZo003G0820 solute carrier family 10 (sodium/bile acid cotransporter family), member 7 protein (SLC10A7) gene, encodes complete protein.EU831744 - Synthetic construct Homo sapiens clone HAIB:100066773; DKFZo003H0220 solute carrier family 10 (sodium/bile acid cotransporter family), member 7 protein (SLC10A7) gene, encodes complete protein.AK075364 - Homo sapiens cDNA PSEC0051 fis, clone NT2RP2000168.CR933647 - Homo sapiens mRNA; cDNA DKFZp313H0531 (from clone DKFZp313H0531).BC150308 - Homo sapiens solute carrier family 10 (sodium/bile acid cotransporter family), member 7, mRNA (cDNA clone MGC:167104 IMAGE:8860437), complete cds.AK126000 - Homo sapiens cDNA FLJ44012 fis, clone TESTI4024874, highly similar to Rattus norvegicus solute carrier family 10 (sodium/bile acid cotransporter family), member 7 (Slc10a7), mRNA.CR936751 - Homo sapiens mRNA; cDNA DKFZp779O2438 (from clone DKFZp779O2438).AK172727 - Homo sapiens cDNA PSEC0026 fis, clone: NT2RP1000434.AY346324 - Homo sapiens SBF-domain containing protein mRNA, complete cds.AK291046 - Homo sapiens cDNA FLJ77110 complete cds.EU831657 - Synthetic construct Homo sapiens clone HAIB:100066686; DKFZo007G0819 solute carrier family 10 (sodium/bile acid cotransporter family), member 7 protein (SLC10A7) gene, encodes complete protein.EU831663 - Synthetic construct Homo sapiens clone HAIB:100066692; DKFZo007H0219 solute carrier family 10 (sodium/bile acid cotransporter family), member 7 protein (SLC10A7) gene, encodes complete protein.DQ122860 - Homo sapiens P7 isoform a (P7) mRNA, complete cds.DQ122861 - Homo sapiens P7 isoform b (P7) mRNA, complete cds.DQ871036 - Homo sapiens P7 isoform c (P7) mRNA, complete cds.KJ903379 - Synthetic construct Homo sapiens clone ccsbBroadEn_12773 SLC10A7 gene, encodes complete protein.BC063471 - Homo sapiens solute carrier family 10 (sodium/bile acid cotransporter family), member 7, mRNA (cDNA clone IMAGE:5210212), complete cds.AL136728 - Homo sapiens mRNA; cDNA DKFZp566M114 (from clone DKFZp566M114).BC148252 - Homo sapiens solute carrier family 10 (sodium/bile acid cotransporter family), member 7, mRNA (cDNA clone IMAGE:40115393), complete cds.BC120970 - Homo sapiens solute carrier family 10 (sodium/bile acid cotransporter family), member 7, mRNA (cDNA clone IMAGE:40115389), complete cds.BC120971 - Homo sapiens solute carrier family 10 (sodium/bile acid cotransporter family), member 7, mRNA (cDNA clone IMAGE:40115390), complete cds.BC127626 - Homo sapiens solute carrier family 10 (sodium/bile acid cotransporter family), member 7, mRNA (cDNA clone IMAGE:40115391), complete cds.BC127627 - Homo sapiens solute carrier family 10 (sodium/bile acid cotransporter family), member 7, mRNA (cDNA clone IMAGE:40115392), complete cds.CU687734 - Synthetic construct Homo sapiens gateway clone IMAGE:100021619 5' read SLC10A7 mRNA.KJ906356 - Synthetic construct Homo sapiens clone ccsbBroadEn_16026 SLC10A7 gene, encodes complete protein.AM392861 - Synthetic construct Homo sapiens clone IMAGE:100001804 for hypothetical protein (C4orf13 gene).BC146684 - Synthetic construct Homo sapiens clone IMAGE:100001804, MGC:165120 solute carrier family 10 (sodium/bile acid cotransporter family), member 7 (SLC10A7) mRNA, encodes complete protein.BC023288 - Homo sapiens solute carrier family 10 (sodium/bile acid cotransporter family), member 7, mRNA (cDNA clone IMAGE:4475169), complete cds.KJ903378 - Synthetic construct Homo sapiens clone ccsbBroadEn_12772 SLC10A7 gene, encodes complete protein.JD251078 - Sequence 232102 from Patent EP1572962.JD423925 - Sequence 404949 from Patent EP1572962.JD363195 - Sequence 344219 from Patent EP1572962.JD205388 - Sequence 186412 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: A7E2E6, A7MAX9, C4orf13, ENST00000432059.1, ENST00000432059.2, ENST00000432059.3, ENST00000432059.4, ENST00000432059.5, NM_001317816, NTCP7_HUMAN, P7, PSEC0051, Q0GE19, Q0VAP9, Q45NG1, Q45NG2, Q5H9S6, Q6P4E6, Q8IZ62, Q8NBP8, Q9H0M9, uc010ipa.1, uc010ipa.2, uc010ipa.3UCSC ID: ENST00000432059.6RefSeq Accession: NM_001317816
Protein: Q0GE19
(aka NTCP7_HUMAN)
CCDS: CCDS34073.1 , CCDS82963.1
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.