Human Gene CYP39A1 (ENST00000619708.4) from GENCODE V44
Description: Homo sapiens cytochrome P450 family 39 subfamily A member 1 (CYP39A1), transcript variant 3, mRNA. (from RefSeq NM_001278739) RefSeq Summary (NM_001278739): This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]. Gencode Transcript: ENST00000619708.4 Gencode Gene: ENSG00000146233.8 Transcript (Including UTRs) Position: hg38 chr6:46,549,580-46,652,830 Size: 103,251 Total Exon Count: 11 Strand: - Coding Region Position: hg38 chr6:46,550,366-46,637,950 Size: 87,585 Coding Exon Count: 9
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
