Human Gene HSPH1 (ENST00000445273.6) from GENCODE V44
Description: Homo sapiens heat shock protein family H (Hsp110) member 1 (HSPH1), transcript variant 4, mRNA. (from RefSeq NM_001286505) RefSeq Summary (NM_001286505): This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers. [provided by RefSeq, Mar 2017]. Gencode Transcript: ENST00000445273.6 Gencode Gene: ENSG00000120694.20 Transcript (Including UTRs) Position: hg38 chr13:31,134,974-31,162,388 Size: 27,415 Total Exon Count: 16 Strand: - Coding Region Position: hg38 chr13:31,137,318-31,162,094 Size: 24,777 Coding Exon Count: 16
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
