ID:PLCL2_HUMAN DESCRIPTION: RecName: Full=Inactive phospholipase C-like protein 2; Short=PLC-L(2); Short=PLC-L2; Short=Phospholipase C-L2; AltName: Full=Phospholipase C-epsilon-2; Short=PLC-epsilon-2; FUNCTION: May play an role in the regulation of Ins(1,4,5)P3 around the endoplasmic reticulum (By similarity). SUBCELLULAR LOCATION: Cytoplasm. Note=Predominantly localized to perinuclear areas in both myoblast and myotube C2C12 cells (By similarity). SIMILARITY: Contains 1 C2 domain. SIMILARITY: Contains 1 PH domain. SIMILARITY: Contains 1 PI-PLC X-box domain. SIMILARITY: Contains 1 PI-PLC Y-box domain. CAUTION: The PI-PLC X-box lacks the essential His at position 486 which is replaced by a Thr and is predicted to be inactive. SEQUENCE CAUTION: Sequence=BAA83044.1; Type=Erroneous initiation; Sequence=BAB14606.1; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9UPR0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
