Human Gene CFAP69 (ENST00000497910.5) from GENCODE V44
  Description: Homo sapiens cilia and flagella associated protein 69 (CFAP69), transcript variant 2, mRNA. (from RefSeq NM_001160138)
Gencode Transcript: ENST00000497910.5
Gencode Gene: ENSG00000105792.19
Transcript (Including UTRs)
   Position: hg38 chr7:90,245,215-90,310,288 Size: 65,074 Total Exon Count: 23 Strand: +
Coding Region
   Position: hg38 chr7:90,245,425-90,310,238 Size: 64,814 Coding Exon Count: 23 

Page IndexSequence and LinksUniProtKB CommentsPrimersRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:90,245,215-90,310,288)mRNA (may differ from genome)Protein (923 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGencodeGeneCardsHPRD
LynxMalacardsMGIneXtProtOMIMPubMed
UniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: CG063_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C7orf63;
SEQUENCE CAUTION: Sequence=BAB14972.1; Type=Erroneous initiation;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 9.38 RPKM in Prostate
Total median expression: 106.57 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -87.70210-0.418 Picture PostScript Text
3' UTR -7.1050-0.142 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR016024 - ARM-type_fold

ModBase Predicted Comparative 3D Structure on A5D8W1
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  AK303034 - Homo sapiens cDNA FLJ52110 complete cds.
AK302636 - Homo sapiens cDNA FLJ52109 complete cds.
BC141834 - Homo sapiens chromosome 7 open reading frame 63, mRNA (cDNA clone MGC:165064 IMAGE:40148850), complete cds.
BC142655 - Homo sapiens chromosome 7 open reading frame 63, mRNA (cDNA clone MGC:164889 IMAGE:40148060), complete cds.
BC140742 - Homo sapiens chromosome 7 open reading frame 63, mRNA (cDNA clone MGC:176419 IMAGE:9021610), complete cds.
KJ899573 - Synthetic construct Homo sapiens clone ccsbBroadEn_08967 C7orf63 gene, encodes complete protein.
BC132771 - Homo sapiens chromosome 7 open reading frame 63, mRNA (cDNA clone IMAGE:40146793), partial cds.
AL833446 - Homo sapiens mRNA; cDNA DKFZp686F18109 (from clone DKFZp686F18109).
AK024715 - Homo sapiens cDNA: FLJ21062 fis, clone CAS01044.
AK093991 - Homo sapiens cDNA FLJ36672 fis, clone UTERU2004073.
AX748399 - Sequence 1924 from Patent EP1308459.
BC036351 - Homo sapiens chromosome 7 open reading frame 63, mRNA (cDNA clone IMAGE:5171041), complete cds.
JD391036 - Sequence 372060 from Patent EP1572962.
JD159581 - Sequence 140605 from Patent EP1572962.
JD262966 - Sequence 243990 from Patent EP1572962.
AY349356 - Homo sapiens unknown mRNA.
JD172165 - Sequence 153189 from Patent EP1572962.
JD450638 - Sequence 431662 from Patent EP1572962.
JD083613 - Sequence 64637 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A3KMP9, A5D8W1, B4DYW6, B4DZP7, B9EIM7, C7orf63, CG063_HUMAN, ENST00000497910.1, ENST00000497910.2, ENST00000497910.3, ENST00000497910.4, NM_001160138, Q6V705, Q8IY89, Q9H7C2, uc011khj.1, uc011khj.2, uc011khj.3
UCSC ID: ENST00000497910.5
RefSeq Accession: NM_001160138
Protein: A5D8W1 (aka CG063_HUMAN)
CCDS: CCDS43613.2, CCDS55122.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.