Human Gene MIR4708 (ENST00000584635.1) from GENCODE V44
  Description: Homo sapiens microRNA 4708 (MIR4708), microRNA. (from RefSeq NR_039857)
RefSeq Summary (NR_039857): microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage.
Gencode Transcript: ENST00000584635.1
Gencode Gene: ENSG00000266740.1
Transcript (Including UTRs)
   Position: hg38 chr14:65,335,117-65,335,183 Size: 67 Total Exon Count: 1 Strand: -


Page IndexSequence and LinksPrimersRNA-Seq ExpressionMicroarray ExpressionOther Species
mRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr14:65,335,117-65,335,183)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGencodeHGNCLynxMalacards
PubMedBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.00 RPKM in Adipose - Subcutaneous
Total median expression: 0.00 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  HZ409512 - JP 2015528002-A/2109: CHIRAL CONTROL.
LG052846 - KR 1020150036642-A/2112: CHIRAL CONTROL.
LP896727 - Sequence 1591 from Patent EP3253886.
FR772977 - Homo sapiens microRNA hsa-miR-4708-3p.
HZ481853 - JP 2015535430-A/2359: TERMINALLY MODIFIED RNA.
HZ791784 - JP 2016504050-A/3529: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JC514516 - Sequence 4769 from Patent WO2014113089.
LF160113 - JP 2016513950-A/179: Oligomers with improved off-target profile.
LP997092 - Sequence 41 from Patent WO2017136662.
LQ072104 - Sequence 2428 from Patent EP2964234.
MA645605 - JP 2017113010-A/3529: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA733489 - JP 2017140048-A/2359: TERMINALLY MODIFIED RNA.
MP073594 - Sequence 41 from Patent WO2018236590.
MP080367 - Sequence 41 from Patent WO2018236589.
HZ482875 - JP 2015535430-A/3381: TERMINALLY MODIFIED RNA.
HZ792806 - JP 2016504050-A/4551: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JC515538 - Sequence 5791 from Patent WO2014113089.
LQ073126 - Sequence 3450 from Patent EP2964234.
MA646627 - JP 2017113010-A/4551: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA734511 - JP 2017140048-A/3381: TERMINALLY MODIFIED RNA.
FR772978 - Homo sapiens microRNA hsa-miR-4708-5p.
HW798991 - WO 2014192907-A/97: Method for detecting miRNA used for differentiating disorders causing motor neuropathy.
HZ481854 - JP 2015535430-A/2360: TERMINALLY MODIFIED RNA.
HZ791785 - JP 2016504050-A/3530: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JC514517 - Sequence 4770 from Patent WO2014113089.
LF161704 - JP 2016513950-A/1770: Oligomers with improved off-target profile.
LQ072105 - Sequence 2429 from Patent EP2964234.
LQ724566 - Sequence 199 from Patent WO2018096084.
MA645606 - JP 2017113010-A/3530: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA733490 - JP 2017140048-A/2360: TERMINALLY MODIFIED RNA.
MA806113 - WO 2018199275-A/373: Kit, device and method for detection of ovary tumor.
MA802658 - JP 2018183181-A/3529: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA805838 - WO 2018199275-A/98: Kit, device and method for detection of ovary tumor.
MA806386 - WO 2018199275-A/646: Kit, device and method for detection of ovary tumor.
MA803680 - JP 2018183181-A/4551: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA802659 - JP 2018183181-A/3530: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA822591 - WO 2019004436-A/404: Kit, device, and method for detection of lung cancer.
MA822255 - WO 2019004436-A/68: Kit, device, and method for detection of lung cancer.
MP168084 - Sequence 91 from Patent EP3469101.
MA822930 - WO 2019004436-A/743: Kit, device, and method for detection of lung cancer.
MB472955 - WO 2019208671-A/354: Kit or device and method for detecting bladder cancer.
MB472720 - WO 2019208671-A/119: Kit or device and method for detecting bladder cancer.
MB473187 - WO 2019208671-A/586: Kit or device and method for detecting bladder cancer.
MB481511 - JP 2019528758-A/91: Methods And Compositions For Prostate Cancer Diagnosis And Treatment.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_039857, uc021ruw.1, uc021ruw.2
UCSC ID: ENST00000584635.1
RefSeq Accession: NR_039857

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.