Human Gene SMIM22 (ENST00000589721.5) from GENCODE V44
  Description: Homo sapiens small integral membrane protein 22 (SMIM22), transcript variant 1, mRNA. (from RefSeq NM_001253790)
Gencode Transcript: ENST00000589721.5
Gencode Gene: ENSG00000267795.6
Transcript (Including UTRs)
   Position: hg38 chr16:4,788,397-4,796,281 Size: 7,885 Total Exon Count: 5 Strand: +
Coding Region
   Position: hg38 chr16:4,795,735-4,796,231 Size: 497 Coding Exon Count: 3 

Page IndexSequence and LinksPrimersRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Other SpeciesmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr16:4,788,397-4,796,281)mRNA (may differ from genome)Protein (83 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGencodeGeneCardsLynx
MGIneXtProtPubMedUniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 47.70 RPKM in Colon - Transverse
Total median expression: 225.14 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -174.10520-0.335 Picture PostScript Text
3' UTR -9.9050-0.198 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  BC035868 - Homo sapiens cDNA clone IMAGE:5172701.
BC048326 - Homo sapiens cDNA clone IMAGE:5166045.
BC128383 - Homo sapiens cDNA clone IMAGE:40120115.
LF210504 - JP 2014500723-A/18007: Polycomb-Associated Non-Coding RNAs.
MA446081 - JP 2018138019-A/18007: Polycomb-Associated Non-Coding RNAs.
KX065456 - Homo sapiens CASIMO1 (CASIMO1) mRNA, complete cds.
BC127921 - Homo sapiens cDNA clone IMAGE:40132487.
BC148245 - Homo sapiens cDNA clone IMAGE:40132490.
BC022385 - Homo sapiens cDNA clone IMAGE:4296365.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000589721.1, ENST00000589721.2, ENST00000589721.3, ENST00000589721.4, K7EJ46, NM_001253790, uc021tcl.1, uc021tcl.2
UCSC ID: ENST00000589721.5
RefSeq Accession: NM_001253790
CCDS: CCDS59258.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.