Human Gene MIR658 (ENST00000385210.1) from GENCODE V44
  Description: Homo sapiens microRNA 658 (MIR658), microRNA. (from RefSeq NR_030395)
RefSeq Summary (NR_030395): microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage.
Gencode Transcript: ENST00000385210.1
Gencode Gene: ENSG00000284197.1
Transcript (Including UTRs)
   Position: hg38 chr22:37,844,272-37,844,371 Size: 100 Total Exon Count: 1 Strand: -


Page IndexSequence and LinksPrimersMicroarray ExpressionOther SpeciesmRNA Descriptions
Other NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr22:37,844,272-37,844,371)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGencodeHGNCLynxMalacards
PubMedBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC014641 - Homo sapiens ankyrin repeat domain 54, mRNA (cDNA clone MGC:15484 IMAGE:2988073), complete cds.
BC066909 - Homo sapiens ankyrin repeat domain 54, mRNA (cDNA clone MGC:87097 IMAGE:4795922), complete cds.
CR456471 - Homo sapiens dJ466N1.4 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.dJ466N1.4.V3).
FV525871 - Nucleic acid controling mast cell degranulation.
HZ408738 - JP 2015528002-A/1335: CHIRAL CONTROL.
HZ462373 - WO 2015190591-A/528: Kit and method for detecting breast cancer.
LG052072 - KR 1020150036642-A/1338: CHIRAL CONTROL.
LY499376 - KR 1020170018412-A/528: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
MS880691 - Sequence 528 from Patent EP3156498.
FV524321 - Nucleic acid controling mast cell degranulation.
FW312418 - DETECTING NUCLEIC ACIDS.
FW364571 - Oligonucleotides for modulating target RNA activity.
HI964809 - Sequence 94 from Patent WO2010139812.
HI965810 - Sequence 130 from Patent WO2010139811.
HI966676 - Sequence 130 from Patent WO2010139810.
HV595483 - JP 2010539959-A/864: Micromirs.
HV938882 - JP 2011519579-A/1710: Oligonucleotides Containing Arabinose Modified Nucleotides For Treating Inflammation and Neoplastic Cell Proliferation.
HV953987 - JP 2012518421-A/899: METHODS OF DETECTING LUNG CANCER.
HW066211 - JP 2013000067-A/3: Composition and Method for Diagnosing Bladder Cancer.
HZ074535 - JP 2013535982-A/626: Single-Stranded RNAi Agents Containing an Internal, Non-Nucleic Acid Spacer.
HZ158040 - JP 2015130862-A/864: Micromirs.
HZ186884 - JP 2015146814-A/633: Oligonucleotides for modulating target RNA activity.
HZ462097 - WO 2015190591-A/252: Kit and method for detecting breast cancer.
HZ482536 - JP 2015535430-A/3042: TERMINALLY MODIFIED RNA.
HZ792467 - JP 2016504050-A/4212: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JA400847 - Sequence 94 from Patent WO2011080318.
JA401825 - Sequence 94 from Patent WO2011080315.
JA402832 - Sequence 94 from Patent WO2011080316.
JA405463 - Sequence 94 from Patent EP2336353.
JA427175 - Sequence 508 from Patent WO2011072177.
JA428989 - Sequence 94 from Patent WO2011095623.
JA660762 - Sequence 216 from Patent WO2011131354.
JA715117 - Sequence 899 from Patent EP2401406.
JA757946 - Sequence 79 from Patent WO2012010584.
JA791902 - Sequence 304 from Patent WO2012089772.
JA792216 - Sequence 265 from Patent WO2012089753.
JA821189 - Sequence 1710 from Patent EP2285961.
JB022217 - Sequence 59 from Patent WO2013026685.
JB022870 - Sequence 124 from Patent WO2013026684.
JB074819 - Sequence 79 from Patent WO2012168448.
JB620720 - Sequence 700 from Patent WO2013063544.
JC037828 - Sequence 356 from Patent EP2643479.
JC515199 - Sequence 5452 from Patent WO2014113089.
JE978771 - Sequence 216 from Patent EP2865765.
LF161224 - JP 2016513950-A/1290: Oligomers with improved off-target profile.
LF632763 - WO 2016117582-A/192: miRNA biomarkers for mental disorders.
LP726436 - Sequence 130 from Patent EP2883966.
LP818706 - Sequence 130 from Patent EP3296406.
LP938648 - Sequence 130 from Patent EP3184651.
LQ072787 - Sequence 3111 from Patent EP2964234.
LQ441072 - Sequence 79 from Patent EP3029157.
LY405548 - KR 1020160117535-A/853: POLY OLIGOMER COMPOUND WITH BIOCLEAVABLE CONJUGATES.
LY499100 - KR 1020170018412-A/252: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LZ234241 - JP 2017184756-A/633: Oligonucleotides for modulating target RNA activity.
MA260787 - JP 2017505623-A/853: POLY OLIGOMER COMPOUND WITH BIOCLEAVABLE CONJUGATES.
MA405895 - WO 2018155427-A/669: A probe with reduced false positive binding, a method to desing the probe, and the use thereof.
MA646288 - JP 2017113010-A/4212: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA734172 - JP 2017140048-A/3042: TERMINALLY MODIFIED RNA.
MS673321 - Sequence 124 from Patent EP3135774.
MS833948 - Sequence 94 from Patent EP3112479.
MS880415 - Sequence 252 from Patent EP3156498.
MS901586 - Sequence 59 from Patent EP3156505.
HZ462678 - WO 2015190591-A/833: Kit and method for detecting breast cancer.
LY499681 - KR 1020170018412-A/833: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
MS880996 - Sequence 833 from Patent EP3156498.
MA806104 - WO 2018199275-A/364: Kit, device and method for detection of ovary tumor.
MA803341 - JP 2018183181-A/4212: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA805828 - WO 2018199275-A/88: Kit, device and method for detection of ovary tumor.
MA806376 - WO 2018199275-A/636: Kit, device and method for detection of ovary tumor.
MA822621 - WO 2019004436-A/434: Kit, device, and method for detection of lung cancer.
MA822284 - WO 2019004436-A/97: Kit, device, and method for detection of lung cancer.
MA822968 - WO 2019004436-A/781: Kit, device, and method for detection of lung cancer.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_030395, uc021wpj.1
UCSC ID: ENST00000385210.1
RefSeq Accession: NR_030395

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.