Human Gene MIR3140 (ENST00000583685.1) from GENCODE V44
  Description: Homo sapiens microRNA 3140 (MIR3140), microRNA. (from RefSeq NR_036092)
RefSeq Summary (NR_036092): microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage.
Gencode Transcript: ENST00000583685.1
Gencode Gene: ENSG00000264678.1
Transcript (Including UTRs)
   Position: hg38 chr4:152,489,327-152,489,416 Size: 90 Total Exon Count: 1 Strand: -


Page IndexSequence and LinksPrimersRNA-Seq ExpressionMicroarray ExpressionOther Species
mRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:152,489,327-152,489,416)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGencodeHGNCLynxPubMed
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.00 RPKM in Adipose - Subcutaneous
Total median expression: 0.00 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  DL491422 - Novel nucleic acids.
HZ409011 - JP 2015528002-A/1608: CHIRAL CONTROL.
LG052345 - KR 1020150036642-A/1611: CHIRAL CONTROL.
HZ074833 - JP 2013535982-A/924: Single-Stranded RNAi Agents Containing an Internal, Non-Nucleic Acid Spacer.
HZ083240 - JP 2015513906-A/597: Stem Cell Microparticles.
HZ437021 - JP 2015529450-A/597: Stem Cell Microparticles.
HZ480106 - JP 2015535430-A/612: TERMINALLY MODIFIED RNA.
HZ790037 - JP 2016504050-A/1782: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JB621018 - Sequence 998 from Patent WO2013063544.
JC172225 - Sequence 597 from Patent WO2013150303.
JC512769 - Sequence 3022 from Patent WO2014113089.
JC573036 - Sequence 597 from Patent WO2014125276.
JC582724 - Sequence 597 from Patent WO2014125277.
JE954420 - Sequence 597 from Patent WO2015052526.
JE956173 - Sequence 597 from Patent WO2015052527.
LF137925 - JP 2016507550-A/597: Method of Producing Microparticles.
LF161112 - JP 2016513950-A/1178: Oligomers with improved off-target profile.
LF162890 - JP 2016513095-A/597: Stem Cell Microparticles and miRNA.
LF953642 - JP 2016534103-A/597: Stem Cell Microparticles and miRNA.
LG005987 - KR 1020150004822-A/597: STEM CELL MICROPARTICLES.
LG053683 - KR 1020150059168-A/597: STEM CELL MICROPARTICLES.
LG240922 - KR 1020160035087-A/597: STEM CELL MICROPARTICLES AND MIRNA.
LQ070357 - Sequence 681 from Patent EP2964234.
LV471007 - JP 2016534036-A/597: Stem Cell Microparticles and miRNA.
MA405567 - WO 2018155427-A/341: A probe with reduced false positive binding, a method to desing the probe, and the use thereof.
MA643858 - JP 2017113010-A/1782: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA731742 - JP 2017140048-A/612: TERMINALLY MODIFIED RNA.
MA765524 - JP 2017514519-A/90: Small ncRNAs as biomarkers.
MP015108 - Sequence 311 from Patent WO2019016252.
FR772731 - Homo sapiens microRNA hsa-miR-3140-3p.
DL490044 - Novel nucleic acids.
FR772732 - Homo sapiens microRNA hsa-miR-3140-5p.
HZ083040 - JP 2015513906-A/397: Stem Cell Microparticles.
HZ436821 - JP 2015529450-A/397: Stem Cell Microparticles.
HZ480107 - JP 2015535430-A/613: TERMINALLY MODIFIED RNA.
HZ790038 - JP 2016504050-A/1783: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JC172025 - Sequence 397 from Patent WO2013150303.
JC512770 - Sequence 3023 from Patent WO2014113089.
JC572836 - Sequence 397 from Patent WO2014125276.
JC582524 - Sequence 397 from Patent WO2014125277.
JE954220 - Sequence 397 from Patent WO2015052526.
JE955973 - Sequence 397 from Patent WO2015052527.
LF137725 - JP 2016507550-A/397: Method of Producing Microparticles.
LF159975 - JP 2016513950-A/41: Oligomers with improved off-target profile.
LF162690 - JP 2016513095-A/397: Stem Cell Microparticles and miRNA.
LF953442 - JP 2016534103-A/397: Stem Cell Microparticles and miRNA.
LG005787 - KR 1020150004822-A/397: STEM CELL MICROPARTICLES.
LG053483 - KR 1020150059168-A/397: STEM CELL MICROPARTICLES.
LG240722 - KR 1020160035087-A/397: STEM CELL MICROPARTICLES AND MIRNA.
LQ070358 - Sequence 682 from Patent EP2964234.
LV470807 - JP 2016534036-A/397: Stem Cell Microparticles and miRNA.
MA643859 - JP 2017113010-A/1783: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA731743 - JP 2017140048-A/613: TERMINALLY MODIFIED RNA.
MA800911 - JP 2018183181-A/1782: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA800912 - JP 2018183181-A/1783: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MP129697 - Sequence 597 from Patent EP3470073.
MP162620 - Sequence 597 from Patent WO2019069093.
MP129497 - Sequence 397 from Patent EP3470073.
MP162420 - Sequence 397 from Patent WO2019069093.
MB031858 - WO 2019093308-A/3: Pharmaceutical Comporision For Use In Cancer Therapy Comprising miRNA.
MB031857 - WO 2019093308-A/2: Pharmaceutical Comporision For Use In Cancer Therapy Comprising miRNA.
MB031856 - WO 2019093308-A/1: Pharmaceutical Comporision For Use In Cancer Therapy Comprising miRNA.
MB118809 - WO 2019107487-A/1: Pharmaceutical composition for treatment of tumor comprising microRNA and derivative thereof as active ingredient.
MB118811 - WO 2019107487-A/3: Pharmaceutical composition for treatment of tumor comprising microRNA and derivative thereof as active ingredient.
MB118812 - WO 2019107487-A/4: Pharmaceutical composition for treatment of tumor comprising microRNA and derivative thereof as active ingredient.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_036092, uc021xtd.1
UCSC ID: ENST00000583685.1
RefSeq Accession: NR_036092

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.