ID:GRID1_MOUSE DESCRIPTION: RecName: Full=Glutamate receptor delta-1 subunit; Short=GluR delta-1 subunit; Flags: Precursor; FUNCTION: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein (By similarity). TISSUE SPECIFICITY: Equally in forebrain and cerebellum. SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRID1 subfamily.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00060 - Ligand-gated ion channel PF00497 - Bacterial extracellular solute-binding proteins, family 3 PF01094 - Receptor family ligand binding region PF10613 - Ligated ion channel L-glutamate- and glycine-binding site
SCOP Domains: 53822 - Periplasmic binding protein-like I 53850 - Periplasmic binding protein-like II
ModBase Predicted Comparative 3D Structure on Q61627
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.