Mouse Gene Bag6 (ENSMUST00000173550.7) Description and Page Index
  Description: Mus musculus BCL2-associated athanogene 6 (Bag6), transcript variant 3, mRNA. (from RefSeq NM_001252469)
Gencode Transcript: ENSMUST00000173550.7
Gencode Gene: ENSMUSG00000024392.17
Transcript (Including UTRs)
   Position: mm10 chr17:35,135,744-35,147,320 Size: 11,577 Total Exon Count: 24 Strand: +
Coding Region
   Position: mm10 chr17:35,136,128-35,147,236 Size: 11,109 Coding Exon Count: 23 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:35,135,744-35,147,320)mRNA (may differ from genome)Protein (1122 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedStanford SOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: G3UZT6_MOUSE
DESCRIPTION: SubName: Full=Large proline-rich protein BAG6;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -27.2083-0.328 Picture PostScript Text
3' UTR -13.9084-0.165 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR021925 - DUF3538
IPR000626 - Ubiquitin
IPR019954 - Ubiquitin_CS
IPR019955 - Ubiquitin_supergroup

Pfam Domains:
PF00240 - Ubiquitin family
PF12057 - Domain of unknown function (DUF3538)
PF13881 - Ubiquitin-2 like Rad60 SUMO-like

SCOP Domains:
101447 - Formin homology 2 domain (FH2 domain)
54236 - Ubiquitin-like

ModBase Predicted Comparative 3D Structure on G3UZT6
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
      
      
 RGD    
 Protein Sequence    
 Alignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0030544 Hsp70 protein binding
GO:0031593 polyubiquitin binding
GO:0070628 proteasome binding

Biological Process:
GO:0001822 kidney development
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007130 synaptonemal complex assembly
GO:0007283 spermatogenesis
GO:0007420 brain development
GO:0009790 embryo development
GO:0030324 lung development
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045861 negative regulation of proteolysis
GO:0050821 protein stabilization
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Cellular Component:
GO:0005634 nucleus
GO:0005829 cytosol


-  Descriptions from all associated GenBank mRNAs
  AK148796 - Mus musculus 2 days neonate sympathetic ganglion cDNA, RIKEN full-length enriched library, clone:7120447D04 product:HLA-B-associated transcript 3, full insert sequence.
BC048137 - Mus musculus HLA-B-associated transcript 3, mRNA (cDNA clone IMAGE:6395739).
BC037051 - Mus musculus HLA-B-associated transcript 3, mRNA (cDNA clone IMAGE:4945855), partial cds.
AK164266 - Mus musculus 9 days embryo whole body cDNA, RIKEN full-length enriched library, clone:D030051D22 product:HLA-B-associated transcript 3, full insert sequence.
AK170134 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630021C15 product:HLA-B-associated transcript 3, full insert sequence.
AK190131 - Mus musculus cDNA, clone:Y1G0101N02, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK192088 - Mus musculus cDNA, clone:Y1G0107N05, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
L76157 - Mus musculus (clone C.1.350(2)) proline rich protein with ubiquitin-like domain (Bat-3) gene, exon.
AK201850 - Mus musculus cDNA, clone:Y1G0139I24, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK217725 - Mus musculus cDNA, clone:Y2G0142M01, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
BC026647 - Mus musculus HLA-B-associated transcript 3, mRNA (cDNA clone IMAGE:4987605), partial cds.
AK200628 - Mus musculus cDNA, clone:Y1G0135E04, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK198776 - Mus musculus cDNA, clone:Y1G0129C14, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK190556 - Mus musculus cDNA, clone:Y1G0103B21, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK193836 - Mus musculus cDNA, clone:Y1G0113I04, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK199983 - Mus musculus cDNA, clone:Y1G0132P17, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK200418 - Mus musculus cDNA, clone:Y1G0134H24, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK192221 - Mus musculus cDNA, clone:Y1G0108D19, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000060247, based on BLAT search.
AK177590 - Mus musculus cDNA, clone:Y0G0103F01, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000060247, based on BLAT search.
AK185524 - Mus musculus cDNA, clone:Y0G0134F19, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000060247, based on BLAT search.
AK212906 - Mus musculus cDNA, clone:Y2G0126I01, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000025250, based on BLAT search.
AK206676 - Mus musculus cDNA, clone:Y2G0105J11, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK206989 - Mus musculus cDNA, clone:Y2G0106J09, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK209757 - Mus musculus cDNA, clone:Y2G0116C06, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK210399 - Mus musculus cDNA, clone:Y2G0118E16, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK211762 - Mus musculus cDNA, clone:Y2G0122M15, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK212866 - Mus musculus cDNA, clone:Y2G0126G01, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK213418 - Mus musculus cDNA, clone:Y2G0128E10, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK215995 - Mus musculus cDNA, clone:Y2G0136N15, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK217539 - Mus musculus cDNA, clone:Y2G0142C04, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK218405 - Mus musculus cDNA, clone:Y2G0145B21, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK219797 - Mus musculus cDNA, clone:Y2G0149K18, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK182155 - Mus musculus cDNA, clone:Y0G0121A09, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK185247 - Mus musculus cDNA, clone:Y0G0133C20, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
BC030296 - Mus musculus HLA-B-associated transcript 3, mRNA (cDNA clone IMAGE:4983728), with apparent retained intron.
AK189151 - Mus musculus cDNA, clone:Y0G0148A15, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK010670 - Mus musculus ES cells cDNA, RIKEN full-length enriched library, clone:2410045D21 product:HLA-B-associated transcript 3, full insert sequence.
AK197287 - Mus musculus cDNA, clone:Y1G0124J24, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK217700 - Mus musculus cDNA, clone:Y2G0142K18, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK218363 - Mus musculus cDNA, clone:Y2G0144P08, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK195759 - Mus musculus cDNA, clone:Y1G0119I17, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK196055 - Mus musculus cDNA, clone:Y1G0120I17, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK208165 - Mus musculus cDNA, clone:Y2G0110F05, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK220145 - Mus musculus cDNA, clone:Y2G0150P17, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.
AK209492 - Mus musculus cDNA, clone:Y2G0115E16, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070358, based on BLAT search.

-  Other Names for This Gene
  Alternate Gene Symbols: G3UZT6, G3UZT6_MOUSE, NM_001252469, uc008cge.1, uc008cge.2, uc008cge.3
UCSC ID: uc008cge.3
RefSeq Accession: NM_001252469
Protein: G3UZT6 CCDS: CCDS57072.1, CCDS57073.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.