Human Gene AGTRAP (ENST00000376627.6) Description and Page Index
  Description: angiotensin II receptor associated protein (from HGNC AGTRAP)
RefSeq Summary (NM_001040197): This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Gencode Transcript: ENST00000376627.6
Gencode Gene: ENSG00000177674.16
Transcript (Including UTRs)
   Position: hg38 chr1:11,736,153-11,750,578 Size: 14,426 Total Exon Count: 7 Strand: +
Coding Region
   Position: hg38 chr1:11,736,209-11,748,593 Size: 12,385 Coding Exon Count: 6 

Page IndexSequence and LinksCTDRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Other SpeciesmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr1:11,736,153-11,750,578)mRNA (may differ from genome)Protein (159 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
MGIPubMedStanford SOURCEUniProtKBWikipedia

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 82.61 RPKM in Whole Blood
Total median expression: 625.31 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -24.0056-0.429 Picture PostScript Text
3' UTR -213.90519-0.412 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Descriptions from all associated GenBank mRNAs
  AK290042 - Homo sapiens cDNA FLJ75423 complete cds, highly similar to Homo sapiens angiotensin II receptor-associated protein (AGTRAP), mRNA.
BC017328 - Homo sapiens angiotensin II receptor-associated protein, mRNA (cDNA clone MGC:29646 IMAGE:4546585), complete cds.
AF312374 - Homo sapiens AGTRAP protein mRNA, complete cds.
E09415 - cDNA encoding a polypeptide obtained from human gliablastoma cells.
BC011946 - Homo sapiens cDNA clone IMAGE:3857985.
JD422171 - Sequence 403195 from Patent EP1572962.
KJ899301 - Synthetic construct Homo sapiens clone ccsbBroadEn_08695 AGTRAP gene, encodes complete protein.
AB528670 - Synthetic construct DNA, clone: pF1KB6809, Homo sapiens AGTRAP gene for angiotensin II receptor-associated protein, without stop codon, in Flexi system.
DQ892619 - Synthetic construct clone IMAGE:100005249; FLH188371.01X; RZPDo839B0873D angiotensin II receptor-associated protein (AGTRAP) gene, encodes complete protein.
DQ895859 - Synthetic construct Homo sapiens clone IMAGE:100010319; FLH188367.01L; RZPDo839B0863D angiotensin II receptor-associated protein (AGTRAP) gene, encodes complete protein.
AF165187 - Homo sapiens ATRAP mRNA, complete cds.
E09414 - cDNA encoding a polypeptide obtained from human gliablastoma cells.
JD384878 - Sequence 365902 from Patent EP1572962.
JD308068 - Sequence 289092 from Patent EP1572962.
JD108561 - Sequence 89585 from Patent EP1572962.
JD274753 - Sequence 255777 from Patent EP1572962.
JD292280 - Sequence 273304 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AK290042, uc057cha.1, X6R9H3
UCSC ID: uc057cha.1
RefSeq Accession: NM_001040197

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.