Human Gene AGTRAP (ENST00000376627.6) Description and Page Index
Description: angiotensin II receptor associated protein (from HGNC AGTRAP) RefSeq Summary (NM_001040197): This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000376627.6 Gencode Gene: ENSG00000177674.16 Transcript (Including UTRs) Position: hg38 chr1:11,736,153-11,750,578 Size: 14,426 Total Exon Count: 7 Strand: + Coding Region Position: hg38 chr1:11,736,209-11,748,593 Size: 12,385 Coding Exon Count: 6
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
AK290042 - Homo sapiens cDNA FLJ75423 complete cds, highly similar to Homo sapiens angiotensin II receptor-associated protein (AGTRAP), mRNA. BC017328 - Homo sapiens angiotensin II receptor-associated protein, mRNA (cDNA clone MGC:29646 IMAGE:4546585), complete cds. AF312374 - Homo sapiens AGTRAP protein mRNA, complete cds. E09415 - cDNA encoding a polypeptide obtained from human gliablastoma cells. BC011946 - Homo sapiens cDNA clone IMAGE:3857985. JD422171 - Sequence 403195 from Patent EP1572962. KJ899301 - Synthetic construct Homo sapiens clone ccsbBroadEn_08695 AGTRAP gene, encodes complete protein. AB528670 - Synthetic construct DNA, clone: pF1KB6809, Homo sapiens AGTRAP gene for angiotensin II receptor-associated protein, without stop codon, in Flexi system. DQ892619 - Synthetic construct clone IMAGE:100005249; FLH188371.01X; RZPDo839B0873D angiotensin II receptor-associated protein (AGTRAP) gene, encodes complete protein. DQ895859 - Synthetic construct Homo sapiens clone IMAGE:100010319; FLH188367.01L; RZPDo839B0863D angiotensin II receptor-associated protein (AGTRAP) gene, encodes complete protein. AF165187 - Homo sapiens ATRAP mRNA, complete cds. E09414 - cDNA encoding a polypeptide obtained from human gliablastoma cells. JD384878 - Sequence 365902 from Patent EP1572962. JD308068 - Sequence 289092 from Patent EP1572962. JD108561 - Sequence 89585 from Patent EP1572962. JD274753 - Sequence 255777 from Patent EP1572962. JD292280 - Sequence 273304 from Patent EP1572962.