Human Gene CAMTA1 (ENST00000467404.6) from GENCODE V44
Description: Homo sapiens calmodulin binding transcription activator 1 (CAMTA1), transcript variant 23, mRNA. (from RefSeq NM_001349627) RefSeq Summary (NM_001349627): The protein encoded by this gene contains a CG1 DNA-binding domain, a transcription factor immunoglobulin domain, ankyrin repeats, and calmodulin-binding IQ motifs. The encoded protein is thought to be a transcription factor and may be a tumor suppressor. However, a translocation event is sometimes observed between this gene and the WWTR1 gene, with the resulting WWTR1-CAMTA1 oncoprotein leading to epithelioid hemangioendothelioma, a malignant vascular cancer. [provided by RefSeq, Mar 2017]. Gencode Transcript: ENST00000467404.6 Gencode Gene: ENSG00000171735.21 Transcript (Including UTRs) Position: hg38 chr1:6,785,518-6,872,019 Size: 86,502 Total Exon Count: 4 Strand: + Coding Region Position: hg38 chr1:6,785,531-6,871,765 Size: 86,235 Coding Exon Count: 4
ID:G3V297_HUMAN DESCRIPTION: SubName: Full=Calmodulin-binding transcription activator 1; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on G3V297
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
