Human Gene TMEM94 (ENST00000579208.5) Description and Page Index
  Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt J3QQW3)
Gencode Transcript: ENST00000579208.5
Gencode Gene: ENSG00000177728.17
Transcript (Including UTRs)
   Position: hg38 chr17:75,456,650-75,499,645 Size: 42,996 Total Exon Count: 24 Strand: +
Coding Region
   Position: hg38 chr17:75,471,906-75,499,334 Size: 27,429 Coding Exon Count: 23 

Page IndexSequence and LinksUniProtKB CommentsRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:75,456,650-75,499,645)mRNA (may differ from genome)Protein (1007 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
EnsemblExonPrimerGeneCardsLynxMGImyGene2
PubMedStanford SOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: J3QQW3_HUMAN
DESCRIPTION: SubName: Full=Uncharacterized protein KIAA0195;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 38.19 RPKM in Brain - Cerebellum
Total median expression: 939.60 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -76.10208-0.366 Picture PostScript Text
3' UTR -129.40311-0.416 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR006068 - ATPase_P-typ_cation-transptr_C
IPR023298 - ATPase_P-typ_TM_dom

Pfam Domains:
PF00689 - Cation transporting ATPase, C-terminus

ModBase Predicted Comparative 3D Structure on J3QQW3
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologGenome BrowserNo ortholog
Gene Details     
Gene Sorter     
MGI   WormBase 
Protein SequenceProtein Sequence  Protein Sequence 
AlignmentAlignment  Alignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  BC042942 - Homo sapiens KIAA0195, mRNA (cDNA clone IMAGE:5295538), with apparent retained intron.
AK304819 - Homo sapiens cDNA FLJ58673 complete cds, highly similar to Transmembrane protein 94.
D83779 - Homo sapiens mRNA for KIAA0195 gene.
BC045540 - Homo sapiens KIAA0195, mRNA (cDNA clone MGC:57170 IMAGE:5274473), complete cds.
AB383792 - Synthetic construct DNA, clone: pF1KSDA0195, Homo sapiens KIAA0195 gene for KIAA0195 protein, complete cds, without stop codon, in Flexi system.
AK316060 - Homo sapiens cDNA, FLJ78959 complete cds, highly similar to Transmembrane protein 94.
AK294526 - Homo sapiens cDNA FLJ58177 complete cds, highly similar to Transmembrane protein 94.
CR936809 - Homo sapiens mRNA; cDNA DKFZp781M1056 (from clone DKFZp781M1056).
AK128508 - Homo sapiens cDNA FLJ46661 fis, clone TRACH3006717.
AK094864 - Homo sapiens cDNA FLJ37545 fis, clone BRCAN2027355.
AK308160 - Homo sapiens cDNA, FLJ98108.
JD203685 - Sequence 184709 from Patent EP1572962.
JD058237 - Sequence 39261 from Patent EP1572962.
JD496022 - Sequence 477046 from Patent EP1572962.
JD057384 - Sequence 38408 from Patent EP1572962.
JD060774 - Sequence 41798 from Patent EP1572962.
JD438998 - Sequence 420022 from Patent EP1572962.
AF070545 - Homo sapiens clone 24581 unknown mRNA.
JD394140 - Sequence 375164 from Patent EP1572962.
JD164993 - Sequence 146017 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: BC042942, J3QQW3, J3QQW3_HUMAN, KIAA0195, uc060jxn.1
UCSC ID: uc060jxn.1
RefSeq Accession: NM_014738
Protein: J3QQW3

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.