Human Gene AC004223.3 (ENST00000593039.5) Description and Page Index
  Description: Homo sapiens RAD51L3-RFFL readthrough (RAD51L3-RFFL), long non-coding RNA. (from RefSeq NR_037714)
RefSeq Summary (NR_037714): This locus represents naturally occurring read-through transcription between the neighboring RAD51-like 3 (RAD51L3) and ring finger and FYVE-like domain containing 1 (RFFL) genes on chromosome 17. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Jan 2011]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK097811.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## readthrough transcript :: includes exons from GeneID 5892, 117584 ##RefSeq-Attributes-END##
Gencode Transcript: ENST00000593039.5
Gencode Gene: ENSG00000267618.5
Transcript (Including UTRs)
   Position: hg38 chr17:35,011,349-35,121,493 Size: 110,145 Total Exon Count: 7 Strand: -
Coding Region
   Position: hg38 chr17:35,011,968-35,121,293 Size: 109,326 Coding Exon Count: 7 

Page IndexSequence and LinksRNA-Seq ExpressionMicroarray ExpressionRNA StructureOther Species
mRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:35,011,349-35,121,493)mRNA (may differ from genome)Protein (272 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGeneCardsMGIPubMedStanford SOURCE
UniProtKB

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.00 RPKM in Adipose - Subcutaneous
Total median expression: 0.00 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -60.40200-0.302 Picture PostScript Text
3' UTR -172.30619-0.278 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  HQ447207 - Synthetic construct Homo sapiens clone IMAGE:100070506; CCSB001869_01 ring finger and FYVE-like domain containing 1 (RFFL) gene, encodes complete protein.
KJ903672 - Synthetic construct Homo sapiens clone ccsbBroadEn_13066 RFFL gene, encodes complete protein.
KJ901694 - Synthetic construct Homo sapiens clone ccsbBroadEn_11088 RAD51D gene, encodes complete protein.
KJ891976 - Synthetic construct Homo sapiens clone ccsbBroadEn_01370 RAD51D gene, encodes complete protein.
KR710457 - Synthetic construct Homo sapiens clone CCSBHm_00012776 RAD51D (RAD51D) mRNA, encodes complete protein.
KR712238 - Synthetic construct Homo sapiens clone CCSBHm_00900197 RAD51D (RAD51D) mRNA, encodes complete protein.
LF209230 - JP 2014500723-A/16733: Polycomb-Associated Non-Coding RNAs.
MA444807 - JP 2018138019-A/16733: Polycomb-Associated Non-Coding RNAs.
BC028424 - Homo sapiens ring finger and FYVE-like domain containing 1, mRNA (cDNA clone MGC:33857 IMAGE:4826613), complete cds.
CR933651 - Homo sapiens mRNA; cDNA DKFZp781O2374 (from clone DKFZp781O2374).
JD048436 - Sequence 29460 from Patent EP1572962.
JD328682 - Sequence 309706 from Patent EP1572962.
AK093112 - Homo sapiens cDNA FLJ35793 fis, clone TESTI2005784, weakly similar to INHIBITOR OF APOPTOSIS PROTEIN.
AX747930 - Sequence 1455 from Patent EP1308459.
AK097811 - Homo sapiens cDNA FLJ40492 fis, clone TESTI2044309, highly similar to DNA REPAIR PROTEIN RAD51.
JD329268 - Sequence 310292 from Patent EP1572962.
JD411403 - Sequence 392427 from Patent EP1572962.
JD228732 - Sequence 209756 from Patent EP1572962.
JD110895 - Sequence 91919 from Patent EP1572962.
JD243844 - Sequence 224868 from Patent EP1572962.
AK308689 - Homo sapiens cDNA, FLJ98730.
BC015681 - Homo sapiens ring finger and FYVE-like domain containing 1, mRNA (cDNA clone IMAGE:4651667), partial cds.
JD206266 - Sequence 187290 from Patent EP1572962.
JD279533 - Sequence 260557 from Patent EP1572962.
DQ590547 - Homo sapiens piRNA piR-57659, complete sequence.
JD335103 - Sequence 316127 from Patent EP1572962.
JD320000 - Sequence 301024 from Patent EP1572962.
JD147740 - Sequence 128764 from Patent EP1572962.
JD217987 - Sequence 199011 from Patent EP1572962.
JD304560 - Sequence 285584 from Patent EP1572962.
JD537534 - Sequence 518558 from Patent EP1572962.
JD520714 - Sequence 501738 from Patent EP1572962.
AF434816 - Homo sapiens fring mRNA, complete cds.
CU688502 - Synthetic construct Homo sapiens gateway clone IMAGE:100018109 5' read RFFL mRNA.
AY098935 - Homo sapiens FYVE-RING finger protein SAKURA mRNA, partial cds.
AB529073 - Synthetic construct DNA, clone: pF1KB4038, Homo sapiens RFFL gene for ring finger and FYVE-like domain containing 1, without stop codon, in Flexi system.
AL117459 - Homo sapiens mRNA; cDNA DKFZp586D0122 (from clone DKFZp586D0122); partial cds.
BX647297 - Homo sapiens mRNA; cDNA DKFZp781L1236 (from clone DKFZp781L1236).
Y15572 - Homo sapiens mRNA for recombination repair protein (R51H3).
AF034956 - Homo sapiens RAD51D mRNA, complete cds.
AB013341 - Homo sapiens mRNA for Trad, complete cds.
AB016223 - Homo sapiens TRAD-d1 mRNA, complete cds.
AB016224 - Homo sapiens TRAD-d2 mRNA, complete cds.
AB016225 - Homo sapiens TRAD-d3 mRNA, complete cds.
AK301249 - Homo sapiens cDNA FLJ53480 complete cds, highly similar to DNA repair protein RAD51 homolog 4.
BC014422 - Homo sapiens RAD51-like 3 (S. cerevisiae), mRNA (cDNA clone MGC:20137 IMAGE:4639227), complete cds.
AK296241 - Homo sapiens cDNA FLJ52930 complete cds, highly similar to DNA repair protein RAD51 homolog 4.
BC002723 - Homo sapiens RAD51-like 3 (S. cerevisiae), mRNA (cDNA clone MGC:3815 IMAGE:3628519), complete cds.
AB020412 - Homo sapiens HsTRAD-d8 mRNA, partial cds.
DQ892318 - Synthetic construct clone IMAGE:100004948; FLH185217.01X; RZPDo839G08146D RAD51-like 3 (S. cerevisiae) (RAD51L3) gene, encodes complete protein.
DQ895520 - Synthetic construct Homo sapiens clone IMAGE:100009980; FLH185214.01L; RZPDo839G08145D RAD51-like 3 (S. cerevisiae) (RAD51L3) gene, encodes complete protein.
AB464124 - Synthetic construct DNA, clone: pF1KB6485, Homo sapiens RAD51L3 gene for RAD51-like 3, without stop codon, in Flexi system.
JD086870 - Sequence 67894 from Patent EP1572962.
JD379874 - Sequence 360898 from Patent EP1572962.
JD386111 - Sequence 367135 from Patent EP1572962.
JD469889 - Sequence 450913 from Patent EP1572962.
JD317631 - Sequence 298655 from Patent EP1572962.
JD098933 - Sequence 79957 from Patent EP1572962.
JD546128 - Sequence 527152 from Patent EP1572962.
JD393199 - Sequence 374223 from Patent EP1572962.
CU678146 - Synthetic construct Homo sapiens gateway clone IMAGE:100022350 5' read RAD51L3 mRNA.
JD469117 - Sequence 450141 from Patent EP1572962.
JD221493 - Sequence 202517 from Patent EP1572962.
AK302450 - Homo sapiens cDNA FLJ55763 complete cds, highly similar to DNA repair protein RAD51 homolog 4.
JD200010 - Sequence 181034 from Patent EP1572962.
JD264036 - Sequence 245060 from Patent EP1572962.
AB018360 - Homo sapiens mRNA for TRAD-d4, partial cds.
AB018361 - Homo sapiens mRNA for TRAD-d5, partial cds.
AB018362 - Homo sapiens mRNA for TRAD-d6, partial cds.
AB018363 - Homo sapiens mRNA for TRAD-d7, partial cds.

-  Other Names for This Gene
  Alternate Gene Symbols: K7EN88, NR_037714, uc002hiq.1, uc002hiq.2, uc002hiq.3
UCSC ID: uc002hiq.3
RefSeq Accession: NR_037714

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.