Human Gene AKAP9 (ENST00000619023.4) Description and Page Index
Description: A-kinase anchoring protein 9 (from HGNC AKAP9) RefSeq Summary (NM_147185): The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq, Aug 2008]. Gencode Transcript: ENST00000619023.4 Gencode Gene: ENSG00000127914.16 Transcript (Including UTRs) Position: hg38 chr7:91,940,916-92,041,781 Size: 100,866 Total Exon Count: 20 Strand: + Coding Region Position: hg38 chr7:91,941,100-92,040,873 Size: 99,774 Coding Exon Count: 20
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.