Human Gene CYP4A22 (ENST00000619754.4) Description and Page Index
Description: Homo sapiens cytochrome P450 family 4 subfamily A member 22 (CYP4A22), transcript variant 2, mRNA. (from RefSeq NM_001308102) RefSeq Summary (NM_001308102): This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]. Gencode Transcript: ENST00000619754.4 Gencode Gene: ENSG00000162365.12 Transcript (Including UTRs) Position: hg38 chr1:47,137,454-47,147,402 Size: 9,949 Total Exon Count: 9 Strand: + Coding Region Position: hg38 chr1:47,137,486-47,146,157 Size: 8,672 Coding Exon Count: 9
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
BC148248 - Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 22, mRNA (cDNA clone MGC:165282 IMAGE:40132876), complete cds. AY280371 - Homo sapiens cytochrome P450 4A22K (CYP4A22) mRNA, complete cds. BC142690 - Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 22, mRNA (cDNA clone MGC:165003 IMAGE:40148647), complete cds. BC142607 - Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 22, mRNA (cDNA clone MGC:164744 IMAGE:40147121), complete cds. KJ904137 - Synthetic construct Homo sapiens clone ccsbBroadEn_13531 CYP4A22 gene, encodes complete protein. AY280372 - Homo sapiens cytochrome P450 4A22 (CYP4A22) mRNA, complete cds. JD532322 - Sequence 513346 from Patent EP1572962. JD526413 - Sequence 507437 from Patent EP1572962. JD371618 - Sequence 352642 from Patent EP1572962. JD110478 - Sequence 91502 from Patent EP1572962. JD051279 - Sequence 32303 from Patent EP1572962. JD436114 - Sequence 417138 from Patent EP1572962. JD053155 - Sequence 34179 from Patent EP1572962. JD184895 - Sequence 165919 from Patent EP1572962. JD493360 - Sequence 474384 from Patent EP1572962. JD146735 - Sequence 127759 from Patent EP1572962. X71480 - H.sapiens Cyp4A-11 mRNA.