Human Gene CCDC82 (ENST00000645500.1) Description and Page Index
  Description: Homo sapiens coiled-coil domain containing 82 (CCDC82), transcript variant 1, mRNA. (from RefSeq NM_001318736)
Gencode Transcript: ENST00000645500.1
Gencode Gene: ENSG00000149231.14
Transcript (Including UTRs)
   Position: hg38 chr11:96,352,779-96,389,948 Size: 37,170 Total Exon Count: 11 Strand: -
Coding Region
   Position: hg38 chr11:96,353,646-96,384,747 Size: 31,102 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr11:96,352,779-96,389,948)mRNA (may differ from genome)Protein (544 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC
HPRDLynxMGIneXtProtPubMedStanford SOURCE

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Coiled-coil domain-containing protein 82;
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SEQUENCE CAUTION: Sequence=BAB15683.1; Type=Frameshift; Positions=527;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 17.84 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 433.36 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -120.70378-0.319 Picture PostScript Text
3' UTR -157.90867-0.182 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR025244 - DUF4196
IPR025451 - DUF4211

Pfam Domains:
PF13846 - Domain of unknown function (DUF4196)
PF13926 - Domain of unknown function (DUF4211)

ModBase Predicted Comparative 3D Structure on Q8N4S0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Descriptions from all associated GenBank mRNAs
  AK027171 - Homo sapiens cDNA: FLJ23518 fis, clone LNG04878.
AK074306 - Homo sapiens cDNA FLJ23726 fis, clone HEP14044.
AF245436 - Homo sapiens HT025 mRNA, complete cds.
JD154677 - Sequence 135701 from Patent EP1572962.
JD062042 - Sequence 43066 from Patent EP1572962.
JD086807 - Sequence 67831 from Patent EP1572962.
JD566496 - Sequence 547520 from Patent EP1572962.
JD312875 - Sequence 293899 from Patent EP1572962.
JD304822 - Sequence 285846 from Patent EP1572962.
JD317111 - Sequence 298135 from Patent EP1572962.
JD082523 - Sequence 63547 from Patent EP1572962.
BC033726 - Homo sapiens coiled-coil domain containing 82, mRNA (cDNA clone MGC:44958 IMAGE:5001231), complete cds.
AK056790 - Homo sapiens cDNA FLJ32228 fis, clone PLACE6004397, highly similar to Coiled-coil domain-containing protein 82.
JD359653 - Sequence 340677 from Patent EP1572962.
JD181515 - Sequence 162539 from Patent EP1572962.
AK314669 - Homo sapiens cDNA, FLJ95516.
EU831803 - Synthetic construct Homo sapiens clone HAIB:100066832; DKFZo008E1121 coiled-coil domain containing 82 protein (CCDC82) gene, encodes complete protein.
EU831880 - Synthetic construct Homo sapiens clone HAIB:100066909; DKFZo004E1122 coiled-coil domain containing 82 protein (CCDC82) gene, encodes complete protein.
BC018663 - Homo sapiens coiled-coil domain containing 82, mRNA (cDNA clone MGC:2462 IMAGE:2964737), complete cds.
JF432455 - Synthetic construct Homo sapiens clone IMAGE:100073667 coiled-coil domain containing 82 (CCDC82) gene, encodes complete protein.
KJ903222 - Synthetic construct Homo sapiens clone ccsbBroadEn_12616 CCDC82 gene, encodes complete protein.
JD396370 - Sequence 377394 from Patent EP1572962.
JD055355 - Sequence 36379 from Patent EP1572962.
AF161533 - Homo sapiens HSPC048 mRNA, complete cds.
AK313893 - Homo sapiens cDNA, FLJ94528, Homo sapiens HSPC048 protein (HSPC048), mRNA.
JD471675 - Sequence 452699 from Patent EP1572962.
JD179952 - Sequence 160976 from Patent EP1572962.
JD472089 - Sequence 453113 from Patent EP1572962.
JD141720 - Sequence 122744 from Patent EP1572962.
JD077367 - Sequence 58391 from Patent EP1572962.
JD109006 - Sequence 90030 from Patent EP1572962.
JD408805 - Sequence 389829 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B3KPU7, CCD82_HUMAN, HT025, NM_001318736, Q8N4S0, Q8WV71, Q9H2Q5, Q9H5E3, uc285jjh.1
UCSC ID: uc285jjh.1
RefSeq Accession: NM_001318736
Protein: Q8N4S0 (aka CCD82_HUMAN)
CCDS: CCDS8307.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.