S. cerevisiae Gene HSP32 (YPL280W)
  Description: Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp33p, and Sno4p member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease
Transcript (Including UTRs)
   Position: sacCer3 chrXVI:11,887-12,600 Size: 714 Total Exon Count: 1 Strand: +
Coding Region
   Position: sacCer3 chrXVI:11,887-12,600 Size: 714 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther SpeciesGO Annotations
Other NamesMethods
Data last updated at UCSC: 2011-08-29

-  Sequence and Links to Tools and Databases
Genomic Sequence (chrXVI:11,887-12,600)mRNAProtein (237 aa)
Gene SorterGenome BrowserOther Species FASTASGDUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Probable chaperone protein HSP32; EC=3.2.-.-; AltName: Full=Heat shock protein 32;
FUNCTION: Probable protease. May act as a chaperone (By similarity).
SIMILARITY: Belongs to the peptidase C56 family.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002818 - ThiJ/PfpI

Pfam Domains:
PF01965 - DJ-1/PfpI family

ModBase Predicted Comparative 3D Structure on Q08992
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanMouseRatZebrafishD. melanogasterC. elegans
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0008234 cysteine-type peptidase activity
GO:0016829 lyase activity
GO:0051082 unfolded protein binding

Biological Process:
GO:0006508 proteolysis
GO:0031669 cellular response to nutrient levels

Cellular Component:
GO:0000932 P-body
GO:0005737 cytoplasm
GO:0010494 cytoplasmic stress granule

-  Other Names for This Gene
Protein: Q08992 (aka HSP32_YEAST)

-  SGD Genes Methods, Credits, and Data Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.