ID:SSU72_HUMAN DESCRIPTION: RecName: Full=RNA polymerase II subunit A C-terminal domain phosphatase SSU72; Short=CTD phosphatase SSU72; EC=3.1.3.16; FUNCTION: May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination. CATALYTIC ACTIVITY: A phosphoprotein + H(2)O = a protein + phosphate. SUBUNIT: Interacts with RB1. Interacts with GTF2B and CD226. SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note=Predominantly in the cytosol. SIMILARITY: Belongs to the SSU72 phosphatase family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9NP77
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.