Human Gene DNMBP (ENST00000543621.6) from GENCODE V44
Description: Homo sapiens dynamin binding protein (DNMBP), transcript variant 3, mRNA. (from RefSeq NM_001318327) RefSeq Summary (NM_001318327): This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]. Gencode Transcript: ENST00000543621.6 Gencode Gene: ENSG00000107554.17 Transcript (Including UTRs) Position: hg38 chr10:99,875,577-99,914,082 Size: 38,506 Total Exon Count: 14 Strand: - Coding Region Position: hg38 chr10:99,877,151-99,914,076 Size: 36,926 Coding Exon Count: 14
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
