Human Gene GSTO1 (ENST00000369713.10) from GENCODE V44
Description: Homo sapiens glutathione S-transferase omega 1 (GSTO1), transcript variant 1, mRNA. (from RefSeq NM_004832) RefSeq Summary (NM_004832): The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]. Gencode Transcript: ENST00000369713.10 Gencode Gene: ENSG00000148834.13 Transcript (Including UTRs) Position: hg38 chr10:104,254,892-104,267,455 Size: 12,564 Total Exon Count: 6 Strand: + Coding Region Position: hg38 chr10:104,254,929-104,267,405 Size: 12,477 Coding Exon Count: 6
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.