Human Gene MAJIN (ENST00000432175.5) from GENCODE V44
  Description: membrane anchored junction protein (from HGNC MAJIN)
Gencode Transcript: ENST00000432175.5
Gencode Gene: ENSG00000168070.12
Transcript (Including UTRs)
   Position: hg38 chr11:64,938,454-64,960,137 Size: 21,684 Total Exon Count: 10 Strand: -
Coding Region
   Position: hg38 chr11:64,939,663-64,959,405 Size: 19,743 Coding Exon Count: 8 

Page IndexSequence and LinksPrimersRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:64,938,454-64,960,137)mRNA (may differ from genome)Protein (216 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblExonPrimerGencodeGeneCardsHPRDLynx
MGIneXtProtPubMedUniProtKB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 13.57 RPKM in Testis
Total median expression: 15.38 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -6.2066-0.094 Picture PostScript Text
3' UTR -27.10121-0.224 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q3KP22
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGDEnsembl   
Protein SequenceProtein SequenceProtein Sequence   
AlignmentAlignmentAlignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003677 DNA binding

Biological Process:
GO:0007129 synapsis
GO:0045141 meiotic telomere clustering
GO:0051321 meiotic cell cycle
GO:0070197 meiotic attachment of telomere to nuclear envelope

Cellular Component:
GO:0000781 chromosome, telomeric region
GO:0000784 nuclear chromosome, telomeric region
GO:0005634 nucleus
GO:0005637 nuclear inner membrane
GO:0005639 integral component of nuclear inner membrane
GO:0005694 chromosome
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  BC033501 - Homo sapiens, clone IMAGE:5171141, mRNA.
AK093130 - Homo sapiens cDNA FLJ35811 fis, clone TESTI2006045.
AX747943 - Sequence 1468 from Patent EP1308459.
BC106951 - Homo sapiens chromosome 11 open reading frame 85, mRNA (cDNA clone MGC:126363 IMAGE:40035116), complete cds.
BC106952 - Homo sapiens chromosome 11 open reading frame 85, mRNA (cDNA clone MGC:126364 IMAGE:40035117), complete cds.
JD262010 - Sequence 243034 from Patent EP1572962.
LC068587 - Homo sapiens MAJIN mRNA for MAJIN, complete cds.
KJ895952 - Synthetic construct Homo sapiens clone ccsbBroadEn_05346 C11orf85 gene, encodes complete protein.

-  Other Names for This Gene
  Alternate Gene Symbols: BC106951, C11orf85, CK085_HUMAN, ENST00000432175.1, ENST00000432175.2, ENST00000432175.3, ENST00000432175.4, Q3KP22, uc001ocb.1, uc001ocb.2
UCSC ID: ENST00000432175.5
RefSeq Accession: NM_001037225
Protein: Q3KP22 (aka CK085_HUMAN)
CCDS: CCDS31603.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.