Human Gene TRIM49 (ENST00000329758.5) Description and Page Index
Description: Homo sapiens tripartite motif containing 49 (TRIM49), mRNA. (from RefSeq NM_020358) RefSeq Summary (NM_020358): The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This gene has been found to be preferentially expressed in testis. Related pseudogenes and gene duplicates have also been identified on chromosome 11. [provided by RefSeq, Aug 2010]. Gencode Transcript: ENST00000329758.5 Gencode Gene: ENSG00000168930.13 Transcript (Including UTRs) Position: hg38 chr11:89,797,655-89,808,575 Size: 10,921 Total Exon Count: 8 Strand: - Coding Region Position: hg38 chr11:89,798,130-89,804,469 Size: 6,340 Coding Exon Count: 6
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P0CI25
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.