ID:KANL2_HUMAN DESCRIPTION: RecName: Full=KAT8 regulatory NSL complex subunit 2; AltName: Full=NSL complex protein NSL2; AltName: Full=Non-specific lethal 2 homolog; FUNCTION: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. SUBUNIT: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1. SUBCELLULAR LOCATION: Nucleus. SEQUENCE CAUTION: Sequence=AAH09746.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAH13900.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA91169.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAB14211.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAD39126.1; Type=Erroneous translation; Note=Wrong choice of CDS;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9H9L4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.