Human Gene TSPAN31 (ENST00000257910.8) from GENCODE V44
Description: Homo sapiens tetraspanin 31 (TSPAN31), transcript variant 1, mRNA. (from RefSeq NM_005981) RefSeq Summary (NM_005981): The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000257910.8 Gencode Gene: ENSG00000135452.10 Transcript (Including UTRs) Position: hg38 chr12:57,745,039-57,750,219 Size: 5,181 Total Exon Count: 6 Strand: + Coding Region Position: hg38 chr12:57,745,155-57,747,290 Size: 2,136 Coding Exon Count: 6
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q12999
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.